{"id":916,"date":"2026-05-28T11:39:13","date_gmt":"2026-05-28T03:39:13","guid":{"rendered":"https:\/\/www.hushentitanium.com\/?p=916"},"modified":"2026-05-28T11:39:13","modified_gmt":"2026-05-28T03:39:13","slug":"why-choose-pharmaceutical-grade-titanium-dioxide-over-food-and-industrial-grades","status":"publish","type":"post","link":"https:\/\/www.hushentitanium.com\/ar\/why-choose-pharmaceutical-grade-titanium-dioxide-over-food-and-industrial-grades\/","title":{"rendered":"\u0644\u0645\u0627\u0630\u0627 \u062a\u062e\u062a\u0627\u0631 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u062f\u0631\u062c\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0648\u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629\u061f"},"content":{"rendered":"<h2 dir=\"auto\"><strong>\u0627\u0644\u062e\u0644\u0627\u0635\u0629<\/strong><\/h2>\n<p data-start=\"83\" data-end=\"475\"><span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/www.hushentitanium.com\/ar\/products\/pharmaceutical-grade-titanium-dioxide\/\"><strong>\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong><\/a><\/span> (TiO\u2082) \u0647\u0648 \u0623\u062d\u062f \u0627\u0644\u0633\u0648\u0627\u063a\u0627\u062a \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0641\u064a \u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629\u060c \u062d\u064a\u062b \u064a\u0648\u0641\u0631 \u0646\u0642\u0627\u0621\u064b \u0641\u0627\u0626\u0642\u064b\u0627 \u0648\u0645\u0631\u0627\u0642\u0628\u0629 \u0635\u0627\u0631\u0645\u0629 \u0644\u0644\u062c\u0648\u062f\u0629 \u0648\u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u062f\u0631\u062c\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0623\u0648 \u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629. \u062a\u0633\u062a\u0639\u0631\u0636 \u0647\u0630\u0647 \u0627\u0644\u0645\u0642\u0627\u0644\u0629 \u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641\u0627\u062a \u0627\u0644\u062a\u0642\u0646\u064a\u0629 \u0648\u0627\u0644\u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0648\u0627\u0644\u0627\u0639\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629 \u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647 \u0641\u064a \u0637\u0644\u0627\u0621 \u0627\u0644\u0623\u0642\u0631\u0627\u0635 \u0648\u062a\u0639\u062a\u064a\u0645 \u0627\u0644\u0643\u0628\u0633\u0648\u0644\u0627\u062a \u0648\u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0625\u0637\u0644\u0627\u0642 \u0627\u0644\u0645\u062a\u062d\u0643\u0645 \u0641\u064a\u0647\u0627.<\/p>\n<p data-start=\"477\" data-end=\"847\">\u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0644\u0635\u0628\u063a\u0629\u060c \u064a\u0639\u0645\u0644 TiO\u2082 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0643\u062d\u0627\u062c\u0632 \u0644\u0644\u0636\u0648\u0621 \u0644\u0644\u0648\u0627\u0642\u064a\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0627\u0644\u0646\u0634\u0637\u0629 \u0627\u0644\u062d\u0633\u0627\u0633\u0629 \u0644\u0644\u0636\u0648\u0621\u060c \u0648\u064a\u062d\u0633\u0646 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0631\u0637\u0648\u0628\u0629\u060c \u0648\u064a\u0636\u0645\u0646 \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u0644\u0648\u0646 \u0639\u0628\u0631 \u0627\u0644\u062f\u0641\u0639\u0627\u062a. \u0648\u064a\u0633\u0627\u0639\u062f \u0641\u0647\u0645 \u0627\u0644\u0641\u0631\u0648\u0642 \u0628\u064a\u0646\u0647 \u0648\u0628\u064a\u0646 \u0627\u0644\u062f\u0631\u062c\u0627\u062a \u0627\u0644\u0642\u064a\u0627\u0633\u064a\u0629 \u0641\u0631\u0642 \u0627\u0644\u0645\u0634\u062a\u0631\u064a\u0627\u062a \u0648\u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0639\u0644\u0649 \u0627\u062a\u062e\u0627\u0630 \u0642\u0631\u0627\u0631\u0627\u062a \u0645\u0633\u062a\u0646\u064a\u0631\u0629 \u0628\u0634\u0623\u0646 \u0627\u0644\u0645\u0635\u0627\u062f\u0631 \u0627\u0644\u062a\u064a \u062a\u0648\u0627\u0632\u0646 \u0628\u064a\u0646 \u0627\u0644\u062a\u0643\u0644\u0641\u0629 \u0648\u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0648\u062c\u0648\u062f\u0629 \u0627\u0644\u0645\u0646\u062a\u062c \u0648\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0645\u0631\u0636\u0649.<\/p>\n<h2 dir=\"auto\"><strong>\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0646\u0642\u0627\u0621 \u0648\u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641\u0627\u062a \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u064a\u0629<\/strong><\/h2>\n<p dir=\"auto\"><strong>\u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0642\u0627\u0628\u0644 \u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0621: \u062d\u062f\u0648\u062f \u0627\u0644\u0645\u0639\u0627\u062f\u0646 \u0627\u0644\u062b\u0642\u064a\u0644\u0629 \u0648\u0645\u0644\u0627\u0645\u062d \u0627\u0644\u0634\u0648\u0627\u0626\u0628<\/strong><\/p>\n<p dir=\"auto\">\u0648\u064a\u0643\u0645\u0646 \u0627\u0644\u0641\u0631\u0642 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0628\u064a\u0646 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645 \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0648\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645 \u0641\u064a \u0627\u0644\u0623\u063a\u0630\u064a\u0629 \u0641\u064a \u0639\u062a\u0628\u0627\u062a \u0627\u0644\u062a\u0644\u0648\u062b \u0628\u0627\u0644\u0645\u0639\u0627\u062f\u0646 \u0627\u0644\u062b\u0642\u064a\u0644\u0629 \u0648\u0628\u0631\u0648\u062a\u0648\u0643\u0648\u0644\u0627\u062a \u0627\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u0634\u0648\u0627\u0626\u0628. \u064a\u062c\u0628 \u0623\u0646 \u064a\u062a\u0648\u0627\u0641\u0642 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645 \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0639 \u0645\u0639\u0627\u064a\u064a\u0631 USP  \u0627\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u0639\u0646\u0635\u0631\u064a\u0629 \u0648\u062f\u0633\u062a\u0648\u0631 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a (EP) 2.4.8\u060c \u0648\u0627\u0644\u062a\u064a \u062a\u0641\u0631\u0636 \u062d\u062f\u0648\u062f\u0627\u064b \u0623\u0643\u062b\u0631 \u0635\u0631\u0627\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u0639\u0646\u0627\u0635\u0631 \u0627\u0644\u0633\u0627\u0645\u0629 \u0645\u0646 \u0644\u0648\u0627\u0626\u062d \u0627\u0644\u0645\u0636\u0627\u0641\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0627\u0644\u0635\u0627\u062f\u0631\u0629 \u0639\u0646 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629.<\/p>\n<p dir=\"auto\"><strong>\u0645\u0642\u0627\u0631\u0646\u0629 \u062d\u062f\u0648\u062f \u0627\u0644\u0645\u0639\u0627\u062f\u0646 \u0627\u0644\u062b\u0642\u064a\u0644\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629:<\/strong><\/p>\n<ul dir=\"auto\">\n<li><strong>\u0627\u0644\u0632\u0631\u0646\u064a\u062e<\/strong>:: \u22643 \u062c\u0632\u0621 \u0641\u064a \u0627\u0644\u0645\u0644\u064a\u0648\u0646 \u0641\u064a \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0642\u0627\u0628\u0644 \u0645\u0627 \u064a\u0635\u0644 \u0625\u0644\u0649 10 \u062c\u0632\u0621 \u0641\u064a \u0627\u0644\u0645\u0644\u064a\u0648\u0646 \u0641\u064a \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629<\/li>\n<li><strong>\u0627\u0644\u0631\u0635\u0627\u0635<\/strong>:: \u22645 \u062c\u0632\u0621 \u0641\u064a \u0627\u0644\u0645\u0644\u064a\u0648\u0646 \u0641\u064a \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0642\u0627\u0628\u0644 10-15 \u062c\u0632\u0621 \u0641\u064a \u0627\u0644\u0645\u0644\u064a\u0648\u0646 \u0641\u064a \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629<\/li>\n<li><strong>\u0627\u0644\u0632\u0626\u0628\u0642 \u0648\u0627\u0644\u0643\u0627\u062f\u0645\u064a\u0648\u0645<\/strong>: \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0623\u0642\u0644 \u0645\u0646 1 \u062c\u0632\u0621 \u0645\u0646 \u0627\u0644\u0645\u0644\u064a\u0648\u0646 \u0627\u0644\u0645\u0637\u0644\u0648\u0628\u0629 \u0644\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/li>\n<\/ul>\n<p dir=\"auto\">\u0648\u0628\u0639\u064a\u062f\u064b\u0627 \u0639\u0646 \u0627\u0644\u0645\u0639\u0627\u062f\u0646 \u0627\u0644\u062b\u0642\u064a\u0644\u0629\u060c \u064a\u062e\u0636\u0639 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0635\u0627\u0631\u0645\u0629 \u0628\u062d\u062b\u064b\u0627 \u0639\u0646 \u0627\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u0639\u0636\u0648\u064a\u0629 \u0648\u0627\u0644\u0645\u0630\u064a\u0628\u0627\u062a \u0627\u0644\u0645\u062a\u0628\u0642\u064a\u0629 \u0648\u0627\u0644\u062a\u0644\u0648\u062b \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a. \u064a\u0631\u0643\u0632 TiO\u2082 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0641\u064a \u0627\u0644\u0645\u0642\u0627\u0645 \u0627\u0644\u0623\u0648\u0644 \u0639\u0644\u0649 \u0646\u0642\u0627\u0621 \u0645\u0624\u0634\u0631 \u0627\u0644\u0644\u0648\u0646 \u0648\u063a\u064a\u0627\u0628 \u0627\u0644\u0645\u0644\u0648\u062b\u0627\u062a \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629\u060c \u0648\u064a\u0641\u062a\u0642\u0631 \u0625\u0644\u0649 \u0627\u0644\u062a\u0646\u0645\u064a\u0637 \u0627\u0644\u0634\u0627\u0645\u0644 \u0644\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u0645\u0637\u0644\u0648\u0628\u0629 \u0644\u0633\u0648\u0627\u063a\u0627\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629. \u0648\u064a\u0635\u0628\u062d \u0647\u0630\u0627 \u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641 \u062d\u0627\u0633\u0645\u064b\u0627 \u0628\u0634\u0643\u0644 \u062e\u0627\u0635 \u0641\u064a \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0627\u0644\u0648\u0631\u064a\u062f\u064a\u0629 \u0623\u0648 \u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0637\u0641\u0627\u0644\u060c \u062d\u064a\u062b \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0624\u062f\u064a \u062d\u062a\u0649 \u0627\u0644\u0645\u0644\u0648\u062b\u0627\u062a \u0627\u0644\u0646\u0632\u0631\u0629 \u0625\u0644\u0649 \u062d\u062f\u0648\u062b \u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0636\u0627\u0631\u0629 \u0623\u0648 \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u0641\u0634\u0644 \u062a\u0646\u0638\u064a\u0645\u064a.<\/p>\n<p dir=\"auto\">\u0648\u064a\u062a\u0645\u064a\u0632 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0623\u064a\u0636\u0627\u064b \u0628\u0628\u0646\u064a\u0629 \u0628\u0644\u0648\u0631\u064a\u0629 \u0623\u0643\u062b\u0631 \u062a\u062d\u0643\u0645\u0627\u064b - \u0623\u0634\u0643\u0627\u0644 \u0627\u0644\u0631\u0648\u062a\u064a\u0644 \u0623\u0648 \u0627\u0644\u0623\u0646\u0627\u062a\u0627\u0632 \u062d\u0635\u0631\u064a\u0627\u064b \u0645\u0639 \u062a\u0631\u0643\u064a\u0628\u0629 \u0637\u0648\u0631 \u062f\u0642\u064a\u0642\u0629. \u0648\u0647\u0630\u0627 \u064a\u0636\u0645\u0646 \u062e\u0635\u0627\u0626\u0635 \u0628\u0635\u0631\u064a\u0629 \u0623\u0641\u0636\u0644 \u0648\u062b\u0628\u0627\u062a\u0627\u064b \u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0627\u064b \u0623\u0641\u0636\u0644 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0627\u0644\u062a\u064a \u0642\u062f \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0623\u0637\u0648\u0627\u0631 \u0645\u062e\u062a\u0644\u0637\u0629.<\/p>\n<figure id=\"attachment_917\" aria-describedby=\"caption-attachment-917\" style=\"width: 480px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-917\" title=\"Pharmaceutical grade titanium dioxide\" src=\"https:\/\/www.hushentitanium.com\/wp-content\/uploads\/2026\/05\/\u5c4f\u5e55\u622a\u56fe-2026-05-28-113622-300x274.jpg\" alt=\"Pharmaceutical grade titanium dioxide\" width=\"480\" height=\"439\" srcset=\"https:\/\/www.hushentitanium.com\/wp-content\/uploads\/2026\/05\/\u5c4f\u5e55\u622a\u56fe-2026-05-28-113622-300x274.jpg 300w, https:\/\/www.hushentitanium.com\/wp-content\/uploads\/2026\/05\/\u5c4f\u5e55\u622a\u56fe-2026-05-28-113622-13x12.jpg 13w, https:\/\/www.hushentitanium.com\/wp-content\/uploads\/2026\/05\/\u5c4f\u5e55\u622a\u56fe-2026-05-28-113622.jpg 466w\" sizes=\"(max-width: 480px) 100vw, 480px\" data-no-translation=\"\" \/><figcaption id=\"caption-attachment-917\" class=\"wp-caption-text\">\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/figcaption><\/figure>\n<h2 dir=\"auto\"><strong>\u062a\u0648\u0632\u064a\u0639 \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0648\u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u0633\u0637\u062d\u064a\u0629<\/strong><\/h2>\n<p dir=\"auto\">\u062a\u062a\u0637\u0644\u0628 \u0627\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u062a\u062d\u0643\u0645\u064b\u0627 \u062f\u0642\u064a\u0642\u064b\u0627 \u0641\u064a \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0644\u0636\u0645\u0627\u0646 \u062a\u0634\u062a\u062a \u0645\u0648\u062d\u062f \u0641\u064a \u0645\u0639\u0644\u0642\u0627\u062a \u0627\u0644\u0637\u0644\u0627\u0621 \u0648\u0643\u062b\u0627\u0641\u0629 \u0628\u0635\u0631\u064a\u0629 \u064a\u0645\u0643\u0646 \u0627\u0644\u062a\u0646\u0628\u0624 \u0628\u0647\u0627.<\/p>\n<p dir=\"auto\"><strong>\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong> \u062a\u0642\u062f\u0645 \u0639\u0627\u062f\u0629\u064b:<\/p>\n<ul dir=\"auto\">\n<li>D50 (\u0645\u062a\u0648\u0633\u0637 \u0642\u0637\u0631 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a): 0.2 - 0.5 \u0645\u064a\u0643\u0631\u0648\u0645\u062a\u0631<\/li>\n<li>\u0645\u0646\u062d\u0646\u064a\u0627\u062a \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u0636\u064a\u0642\u0629 (\u0646\u0633\u0628\u0629 D90\/D10 &lt;3.0)<\/li>\n<li>\u062e\u0635\u0627\u0626\u0635 \u0645\u0645\u062a\u0627\u0632\u0629 \u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u062a\u0643\u062a\u0644 \u0648\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u062a\u0631\u0633\u064a\u0628<\/li>\n<\/ul>\n<p dir=\"auto\">\u0648\u0639\u0644\u0649 \u0627\u0644\u0646\u0642\u064a\u0636 \u0645\u0646 \u0630\u0644\u0643\u060c \u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u064a\u0633\u062a\u062e\u062f\u0645 TiO\u2082 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u062c\u0633\u064a\u0645\u0627\u062a \u0623\u0643\u062b\u0631 \u062e\u0634\u0648\u0646\u0629 (D50 &gt; 1.0 \u0645\u064a\u0643\u0631\u0648\u0645\u062a\u0631)\u060c \u0648\u0647\u064a \u0645\u0646\u0627\u0633\u0628\u0629 \u0644\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0648\u0644\u0643\u0646\u0647\u0627 \u063a\u064a\u0631 \u0645\u0644\u0627\u0626\u0645\u0629 \u0644\u0644\u0637\u0644\u0627\u0621\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0630\u0627\u062a \u0627\u0644\u0623\u063a\u0634\u064a\u0629 \u0627\u0644\u0631\u0642\u064a\u0642\u0629 \u062d\u064a\u062b \u064a\u0624\u062b\u0631 \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0628\u0634\u0643\u0644 \u0645\u0628\u0627\u0634\u0631 \u0639\u0644\u0649 \u062a\u0648\u062d\u064a\u062f \u0627\u0644\u0637\u0644\u0627\u0621 \u0648\u062d\u0631\u0643\u064a\u0629 \u0627\u0644\u0630\u0648\u0628\u0627\u0646.<\/p>\n<p dir=\"auto\">\u062a\u064f\u0639\u062f \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u0633\u0637\u062d\u064a\u0629 \u0639\u0627\u0645\u0644 \u062a\u0645\u064a\u064a\u0632 \u062d\u0627\u0633\u0645 \u0622\u062e\u0631. \u064a\u062a\u0644\u0642\u0649 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0637\u0644\u0627\u0621\u0627\u062a \u0645\u062a\u062e\u0635\u0635\u0629 \u0645\u0646 \u0627\u0644\u0623\u0644\u0648\u0645\u064a\u0646\u0627 \u0648\u0627\u0644\u0633\u064a\u0644\u064a\u0643\u0627 (\u0639\u0627\u062f\u0629\u064b \u0645\u0627 \u062a\u0643\u0648\u0646 2-4% \u0628\u0627\u0644\u0648\u0632\u0646\/\u0627\u0644\u0648\u0632\u0646). \u0647\u0630\u0647 \u0627\u0644\u0637\u0644\u0627\u0621\u0627\u062a:<\/p>\n<ul dir=\"auto\">\n<li>\u062a\u062b\u0628\u064a\u062a \u0633\u0637\u062d \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0636\u062f \u0627\u0644\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0648\u0627\u0633\u0639\u0629 \u0641\u064a \u0627\u0644\u0623\u0633 \u0627\u0644\u0647\u064a\u062f\u0631\u0648\u062c\u064a\u0646\u064a<\/li>\n<li>\u0645\u0646\u0639 \u0646\u0634\u0627\u0637 \u0627\u0644\u062a\u062d\u0641\u064a\u0632 \u0627\u0644\u0636\u0648\u0626\u064a \u0627\u0644\u0630\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u062d\u0644\u0644 \u0645\u0643\u0648\u0646\u0627\u062a API \u0627\u0644\u062d\u0633\u0627\u0633\u0629<\/li>\n<li>\u062a\u062d\u0633\u064a\u0646 \u0642\u0627\u0628\u0644\u064a\u0629 \u0627\u0644\u062a\u0634\u062a\u062a \u0641\u064a \u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0637\u0644\u0627\u0621 \u0627\u0644\u0645\u0627\u0626\u064a \u0648\u0627\u0644\u0639\u0636\u0648\u064a<\/li>\n<li>\u062a\u0639\u0632\u064a\u0632 \u0627\u0644\u062a\u0648\u0627\u0641\u0642 \u0645\u0639 \u0627\u0644\u0628\u0648\u0644\u064a\u0645\u0631\u0627\u062a \u0645\u062b\u0644 HPMC \u0648PVA \u0648\u0625\u064a\u062b\u064a\u0644 \u0627\u0644\u0633\u0644\u064a\u0644\u0648\u0632<\/li>\n<\/ul>\n<p dir=\"auto\">\u0648\u0639\u0627\u062f\u0629\u064b \u0645\u0627 \u062a\u0641\u062a\u0642\u0631 \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0639\u0627\u062f\u0629\u064b \u0625\u0644\u0649 \u0645\u062b\u0644 \u0647\u0630\u0647 \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0627\u0644\u0633\u0637\u062d\u064a\u0629 \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629\u060c \u0645\u0645\u0627 \u0642\u062f \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u062a\u0648\u0627\u0641\u0642 \u0648\u0627\u0646\u062e\u0641\u0627\u0636 \u062b\u0628\u0627\u062a \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0629.<\/p>\n<table style=\"border-collapse: collapse; width: 100%; border: 1px solid #000;\">\n<thead>\n<tr>\n<th style=\"border: 1px solid #000; padding: 8px; background-color: #eee;\"><strong>\u0627\u0644\u0645\u0639\u0644\u0645\u0629<\/strong><\/th>\n<th style=\"border: 1px solid #000; padding: 8px; background-color: #eee;\"><strong>\u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong><\/th>\n<th style=\"border: 1px solid #000; padding: 8px; background-color: #eee;\"><strong>\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0621<\/strong><\/th>\n<th style=\"border: 1px solid #000; padding: 8px; background-color: #eee;\"><strong>\u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u0627\u0644\u0646\u0642\u0627\u0621 (\u0645\u062d\u062a\u0648\u0649 TiO\u2082)<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u226599.0%<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u226598.01.0%<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u226592.0%<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u0627\u0644\u0632\u0631\u0646\u064a\u062e (\u062c\u0632\u0621 \u0641\u064a \u0627\u0644\u0645\u0644\u064a\u0648\u0646)<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u22643<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u226410<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u063a\u064a\u0631 \u0645\u062d\u062f\u062f<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u0627\u0644\u0631\u0635\u0627\u0635 (\u062c\u0632\u0621 \u0641\u064a \u0627\u0644\u0645\u0644\u064a\u0648\u0646)<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u22645<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u226410-15<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u226450<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u0627\u0644\u0632\u0626\u0628\u0642 (\u062c\u0632\u0621 \u0645\u0646 \u0627\u0644\u0645\u0644\u064a\u0648\u0646)<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u22641<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u22643<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u063a\u064a\u0631 \u0645\u062d\u062f\u062f<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a D50 (\u0645\u064a\u0643\u0631\u0648\u0645\u062a\u0631)<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">0.2-0.5<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">0.8-1.5<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">1.0-5.0<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u0633\u0637\u062d\u064a\u0629<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u0623\u0644\u0648\u0645\u064a\u0646\u0627\/\u0633\u064a\u0644\u064a\u0643\u0627 (\u062f\u0631\u062c\u0629 \u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629)<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u0627\u062e\u062a\u064a\u0627\u0631\u064a<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u0644\u0627 \u0634\u064a\u0621 \u0623\u0648 \u0627\u0644\u0637\u0644\u0627\u0621\u0627\u062a \u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u0627\u0644\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0645\u0637\u0628\u0642\u0629<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u0628\u0631\u0646\u0627\u0645\u062c \u0627\u0644\u0623\u0645\u0645 \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0644\u0644\u0628\u064a\u0626\u0629 \u060c \u0628\u0631\u0648\u062a\u0648\u0643\u0648\u0644 \u0645\u0648\u0646\u062a\u0631\u064a\u0627\u0644 2.4.8\u060c JP XVII<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">FDA 21 CFR 73.575<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">ASTM D476<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #000; padding: 8px;\"><strong>\u0627\u0644\u062d\u062f\u0648\u062f \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0629<\/strong><\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u0625\u062c\u0645\u0627\u0644\u064a \u0627\u0644\u062a\u0639\u062f\u0627\u062f \u0627\u0644\u0647\u0648\u0627\u0626\u064a &lt;100 CFU\/g<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">&lt;\u0623\u0642\u0644 \u0645\u0646 1000 \u0648\u062d\u062f\u0629 \u0643\u0631\u0648\u0641\u0648\/\u063a\u0631\u0627\u0645<\/td>\n<td style=\"border: 1px solid #000; padding: 8px;\">\u063a\u064a\u0631 \u0645\u062d\u062f\u062f<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<hr \/>\n<h2 dir=\"auto\"><strong>\u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a \u0648\u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u062a\u0648\u062b\u064a\u0642<\/strong><\/h2>\n<h3 dir=\"auto\"><strong>\u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629: \u0645\u0648\u0627\u0621\u0645\u0629 USP \u0648 EP \u0648 JP<\/strong><\/h3>\n<p dir=\"auto\"><strong>\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong> \u064a\u062c\u0628 \u0623\u0646 \u062a\u0641\u064a \u0628\u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0628\u0631 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u062f\u0633\u0627\u062a\u064a\u0631 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0644\u062f\u0639\u0645 \u0627\u0644\u062a\u0633\u062c\u064a\u0644 \u0627\u0644\u0639\u0627\u0644\u0645\u064a \u0644\u0644\u0623\u062f\u0648\u064a\u0629. \u0648\u062a\u062d\u062f\u062f \u062f\u0631\u0627\u0633\u0629 \u062f\u0633\u062a\u0648\u0631 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a (USP) \u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u0647\u0648\u064a\u0629 (\u062d\u064a\u0648\u062f \u0627\u0644\u0623\u0634\u0639\u0629 \u0627\u0644\u0633\u064a\u0646\u064a\u0629 \u0648\u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u0637\u064a\u0641\u064a \u0628\u0627\u0644\u0623\u0634\u0639\u0629 \u062a\u062d\u062a \u0627\u0644\u062d\u0645\u0631\u0627\u0621) \u0648\u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u0646\u0642\u0627\u0621 \u0648\u062d\u062f\u0648\u062f \u0627\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u0623\u0648\u0644\u064a\u0629 \u0627\u0644\u0645\u062a\u0648\u0627\u0641\u0642\u0629 \u0645\u0639 \u0625\u0631\u0634\u0627\u062f\u0627\u062a ICH Q3D. \u062a\u062d\u0627\u0641\u0638 \u062f\u0633\u0627\u062a\u064a\u0631 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 (EP) \u0648\u062f\u0633\u062a\u0648\u0631 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u0627\u0628\u0627\u0646\u064a (JP) \u0639\u0644\u0649 \u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0645\u0646\u0633\u0642\u0629 \u0648\u0644\u0643\u0646\u0647\u0627 \u063a\u064a\u0631 \u0645\u062a\u0637\u0627\u0628\u0642\u0629\u060c \u0645\u0645\u0627 \u064a\u062a\u0637\u0644\u0628 \u0645\u0646 \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0625\u062b\u0628\u0627\u062a \u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0627\u0644\u0643\u0627\u0645\u0644 \u0641\u064a \u062c\u0645\u064a\u0639 \u0627\u0644\u062f\u0633\u0627\u062a\u064a\u0631 \u0630\u0627\u062a \u0627\u0644\u0635\u0644\u0629.<\/p>\n<p dir=\"auto\"><strong>\u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u062a\u0648\u062b\u064a\u0642 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0644\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629:<\/strong><\/p>\n<ul dir=\"auto\">\n<li><strong>\u0634\u0647\u0627\u062f\u0629 \u0627\u0644\u062a\u062d\u0644\u064a\u0644 (CoA)<\/strong>: \u064a\u062c\u0628 \u0623\u0646 \u062a\u062a\u0636\u0645\u0646 \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0627\u0644\u062f\u0641\u0639\u0629 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0645\u0639\u0627\u062f\u0646 \u0627\u0644\u062b\u0642\u064a\u0644\u0629\u060c \u0648\u062a\u0648\u0632\u064a\u0639 \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a\u060c \u0648\u0627\u0644\u0641\u0627\u0642\u062f \u0639\u0646\u062f \u0627\u0644\u062a\u062c\u0641\u064a\u0641\u060c \u0648\u062f\u0631\u062c\u0629 \u0627\u0644\u062d\u0645\u0648\u0636\u0629 \u0641\u064a \u0627\u0644\u0645\u0639\u0644\u0642 \u0627\u0644\u0645\u0627\u0626\u064a\u060c \u0648\u0627\u0644\u062a\u0644\u0648\u062b \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a. \u064a\u062c\u0628 \u0623\u0646 \u062a\u0634\u064a\u0631 \u0643\u0644 \u0645\u0639\u0644\u0645\u0629 \u0625\u0644\u0649 \u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 (USP\u060c \u0623\u0648 EP\u060c \u0623\u0648 \u0637\u0631\u064a\u0642\u0629 \u062f\u0627\u062e\u0644\u064a\u0629 \u0645\u0639\u062a\u0645\u062f\u0629).<\/li>\n<li><strong>\u0627\u0644\u0645\u0644\u0641 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u0644\u0645\u062e\u062f\u0631\u0627\u062a (DMF)<\/strong>: \u064a\u0648\u0641\u0631 \u0646\u0645\u0648\u0630\u062c \u0646\u0645\u0648\u0630\u062c DMF \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a \u0627\u0644\u0645\u0648\u062f\u0639 \u0644\u062f\u0649 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0648\u0627\u0644\u0648\u0643\u0627\u0644\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 \u0644\u0644\u0623\u062f\u0648\u064a\u0629 \u0648\u0627\u0644\u0648\u0643\u0627\u0644\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 \u0644\u0644\u0623\u062f\u0648\u064a\u0629 \u0648\u0627\u0644\u0648\u0643\u0627\u0644\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 \u0644\u0644\u0623\u062f\u0648\u064a\u0629 \u062a\u0641\u0627\u0635\u064a\u0644 \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u0633\u0631\u064a\u0629 \u0648\u0625\u062c\u0631\u0627\u0621\u0627\u062a \u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u062c\u0648\u062f\u0629 \u0648\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062b\u0628\u0627\u062a. \u064a\u062c\u0628 \u0639\u0644\u0649 \u0645\u0634\u062a\u0631\u064a \u0627\u0644\u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0627\u0644\u062a\u062d\u0642\u0642 \u062f\u0627\u0626\u0645\u064b\u0627 \u0645\u0646 \u0623\u0646 \u0646\u0645\u0648\u0630\u062c \u0646\u0645\u0648\u0630\u062c DMF \u0633\u0627\u0631\u064a \u0627\u0644\u0645\u0641\u0639\u0648\u0644 \u0648\u0633\u0627\u0631\u064a \u0627\u0644\u0645\u0641\u0639\u0648\u0644.<\/li>\n<li><strong>\u0633\u062c\u0644\u0627\u062a \u062a\u062a\u0628\u0639 \u0627\u0644\u062f\u064f\u0641\u0639\u0627\u062a<\/strong>: \u0633\u0644\u0633\u0644\u0629 \u0643\u0627\u0645\u0644\u0629 \u0645\u0646 \u0627\u0644\u062d\u064a\u0627\u0632\u0629 \u0628\u062f\u0621\u0627\u064b \u0645\u0646 \u0645\u0635\u0627\u062f\u0631 \u062e\u0627\u0645 \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0627\u0644\u062e\u0627\u0645 \u0645\u0631\u0648\u0631\u0627\u064b \u0628\u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0648\u062d\u062a\u0649 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0646\u0647\u0627\u0626\u064a \u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u062c\u0648\u062f\u0629.<\/li>\n<\/ul>\n<p dir=\"auto\">\u0648\u0639\u0627\u062f\u0629\u064b \u0645\u0627 \u062a\u0642\u062f\u0645 \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0639\u0627\u062f\u0629\u064b \u0636\u0645\u0627\u0646\u0627\u062a \u062a\u0648\u0627\u0641\u0642\u064a\u0629 \u0645\u0628\u0633\u0637\u0629 \u062a\u0631\u0643\u0632 \u0641\u0642\u0637 \u0639\u0644\u0649 \u0645\u0624\u0634\u0631 \u0627\u0644\u0644\u0648\u0646 \u0648\u0627\u0644\u0646\u0642\u0627\u0621 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u060c \u0648\u062a\u0641\u062a\u0642\u0631 \u0625\u0644\u0649 \u0627\u0644\u062a\u0648\u062b\u064a\u0642 \u0627\u0644\u0634\u0627\u0645\u0644 \u0627\u0644\u0645\u0637\u0644\u0648\u0628 \u0644\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629.<\/p>\n<h3 dir=\"auto\"><strong>\u0627\u0644\u062a\u0632\u0627\u0645\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0641\u064a \u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f\u0629 \u0648\u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f\u0629 \u0648\u0627\u0644\u062a\u0632\u0627\u0645\u0627\u062a \u0627\u0644\u062a\u062f\u0642\u064a\u0642<\/strong><\/h3>\n<p dir=\"auto\">\u0625\u0646 \u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0644\u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f\u0629 (GMP) \u0647\u0648 \u0645\u0627 \u064a\u0645\u064a\u0632 \u062d\u0642\u064b\u0627 <strong>\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong> \u0627\u0644\u0625\u0646\u062a\u0627\u062c \u0645\u0646 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0623\u0648 \u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629. \u064a\u062c\u0628 \u0623\u0646 \u064a\u0639\u0645\u0644 \u0627\u0644\u0645\u0635\u0646\u0639\u0648\u0646 \u0628\u0645\u0648\u062c\u0628 \u0644\u0648\u0627\u0626\u062d \u0635\u0627\u0631\u0645\u0629 \u0644\u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 21 CFR \u0627\u0644\u062c\u0632\u0621 211 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0648\u0627\u0644\u0645\u062c\u0644\u062f 4 \u0645\u0646 EudraLex \u0641\u064a \u0627\u0644\u0627\u062a\u062d\u0627\u062f \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a.<\/p>\n<p dir=\"auto\"><strong>\u062a\u062a\u0636\u0645\u0646 \u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f \u0627\u0644\u062d\u0631\u062c\u0629 \u0645\u0627 \u064a\u0644\u064a:<\/strong><\/p>\n<ul dir=\"auto\">\n<li>\u0627\u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u0628\u064a\u0626\u064a\u0629 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u062a\u0631\u0634\u064a\u062d HEPA<\/li>\n<li>\u062a\u062f\u0631\u064a\u0628 \u0627\u0644\u0645\u0648\u0638\u0641\u064a\u0646 \u0648\u0628\u0631\u0648\u062a\u0648\u0643\u0648\u0644\u0627\u062a \u0627\u0644\u0646\u0638\u0627\u0641\u0629 \u0627\u0644\u0635\u062d\u064a\u0629<\/li>\n<li>\u062a\u0623\u0647\u064a\u0644 \u0627\u0644\u0645\u0639\u062f\u0627\u062a \u0648\u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0635\u0644\u0627\u062d\u064a\u0629 \u0627\u0644\u0645\u0639\u062f\u0627\u062a \u0648\u0627\u0644\u062a\u0646\u0638\u064a\u0641<\/li>\n<li>\u0645\u0646\u0627\u0637\u0642 \u0625\u0646\u062a\u0627\u062c \u0645\u0646\u0641\u0635\u0644\u0629 \u0644\u0645\u0646\u0639 \u0627\u0644\u062a\u0644\u0648\u062b \u0627\u0644\u062a\u0628\u0627\u062f\u0644\u064a<\/li>\n<li>\u0623\u0646\u0638\u0645\u0629 \u0642\u0648\u064a\u0629 \u0644\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u062a\u063a\u064a\u064a\u0631 \u0648\u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641<\/li>\n<\/ul>\n<p dir=\"auto\">\u064a\u062c\u0628 \u0623\u0646 \u062a\u0642\u064a\u0645 \u0639\u0645\u0644\u064a\u0627\u062a \u062a\u062f\u0642\u064a\u0642 \u062a\u0623\u0647\u064a\u0644 \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0628\u062f\u0642\u0629 \u062a\u0635\u0645\u064a\u0645 \u0627\u0644\u0645\u0646\u0634\u0623\u0629 \u0648\u062a\u062f\u0627\u0628\u064a\u0631 \u0645\u0643\u0627\u0641\u062d\u0629 \u0627\u0644\u062a\u0644\u0648\u062b \u0648\u0625\u062c\u0631\u0627\u0621\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0641 \u0627\u0644\u0645\u0648\u062b\u0642\u0629. \u064a\u062c\u0628 \u0623\u0646 \u062a\u062b\u0628\u062a \u0627\u0644\u0645\u0646\u0634\u0622\u062a \u0627\u0644\u0645\u0646\u062a\u062c\u0629 \u0644\u0644\u062f\u0631\u062c\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629 \u0639\u0644\u0649 \u062d\u062f \u0633\u0648\u0627\u0621 \u0628\u0631\u0648\u062a\u0648\u0643\u0648\u0644\u0627\u062a \u062a\u0628\u062f\u064a\u0644 \u0641\u0639\u0627\u0644\u0629 \u0648\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0645\u062e\u0644\u0641\u0627\u062a.<\/p>\n<p dir=\"auto\">\u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u0627\u0644\u0633\u0646\u0648\u064a\u0629 \u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u0645\u0646\u062a\u062c (APQRs) \u0636\u0631\u0648\u0631\u064a\u0629. \u062a\u062c\u0645\u0639 \u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u0628\u064a\u0627\u0646\u0627\u062a \u062d\u0648\u0644 \u0633\u0645\u0627\u062a \u0627\u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u062d\u0631\u062c\u0629 \u0648\u0627\u0644\u0623\u062d\u062f\u0627\u062b \u063a\u064a\u0631 \u0627\u0644\u0645\u0637\u0627\u0628\u0642\u0629 \u0644\u0644\u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0648\u0634\u0643\u0627\u0648\u0649 \u0627\u0644\u0639\u0645\u0644\u0627\u0621. \u064a\u062c\u0628 \u0639\u0644\u0649 \u0645\u0634\u062a\u0631\u064a \u0627\u0644\u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0637\u0644\u0628 \u0645\u0644\u062e\u0635\u0627\u062a \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u0627\u0644\u0633\u0646\u0648\u064a\u0629 \u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u0645\u0646\u062a\u062c \u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644.<\/p>\n<h2 dir=\"auto\"><strong>\u0627\u0644\u0623\u062f\u0627\u0621 \u0627\u0644\u062e\u0627\u0635 \u0628\u0627\u0644\u062a\u0637\u0628\u064a\u0642 \u0641\u064a \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629<\/strong><\/h2>\n<h3 dir=\"auto\"><strong>\u0637\u0644\u0627\u0621 \u0627\u0644\u063a\u0634\u0627\u0621 \u0648\u0627\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u062a\u0639\u062a\u064a\u0645 \u0641\u064a \u0623\u0634\u0643\u0627\u0644 \u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0627\u0644\u0635\u0644\u0628\u0629<\/strong><\/h3>\n<p dir=\"auto\"><strong>\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong> \u064a\u0639\u0645\u0644 \u0643\u0639\u0627\u0645\u0644 \u0627\u0644\u062a\u0639\u062a\u064a\u0645 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0641\u064a \u0627\u0644\u0623\u0642\u0631\u0627\u0635 \u0627\u0644\u0645\u063a\u0644\u0641\u0629 \u0628\u0627\u0644\u0623\u0641\u0644\u0627\u0645. \u0648\u064a\u0648\u0641\u0631 \u062d\u0645\u0627\u064a\u0629 \u0623\u0633\u0627\u0633\u064a\u0629 \u0645\u0646 \u0627\u0644\u0636\u0648\u0621 \u0644\u0645\u0643\u0648\u0646\u0627\u062a API \u0627\u0644\u062d\u0633\u0627\u0633\u0629 \u0644\u0644\u0636\u0648\u0621 \u0645\u0639 \u062a\u0645\u0643\u064a\u0646 \u062a\u0645\u064a\u064a\u0632 \u0627\u0644\u0639\u0644\u0627\u0645\u0629 \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062a\u062e\u0635\u064a\u0635 \u0627\u0644\u062f\u0642\u064a\u0642 \u0644\u0644\u0623\u0644\u0648\u0627\u0646. \u062a\u0634\u062a\u0645\u0644 \u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0627\u0644\u0637\u0644\u0627\u0621 \u0639\u0627\u062f\u0629\u064b \u0639\u0644\u0649 10-30% TiO\u2082 (\u0648\u0632\u0646\/\u0648\u0632\u0646 \u0645\u0646 \u0627\u0644\u0628\u0648\u0644\u064a\u0645\u0631 \u0627\u0644\u062c\u0627\u0641)\u060c \u0627\u0639\u062a\u0645\u0627\u062f\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u0639\u062a\u0627\u0645\u0629 \u0627\u0644\u0645\u0637\u0644\u0648\u0628\u0629 \u0648\u0633\u0645\u0627\u0643\u0629 \u0627\u0644\u0637\u0644\u0627\u0621 \u0648\u0644\u0648\u0646 \u0627\u0644\u0637\u0628\u0642\u0629 \u0627\u0644\u062a\u062d\u062a\u064a\u0629.<\/p>\n<p dir=\"auto\"><strong>\u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0641\u064a \u0637\u0644\u0627\u0621 \u0627\u0644\u0641\u064a\u0644\u0645:<\/strong><\/p>\n<ul dir=\"auto\">\n<li>\u062d\u0645\u0627\u064a\u0629 \u0641\u0627\u0626\u0642\u0629 \u0644\u0644\u062d\u0627\u062c\u0632 \u0627\u0644\u0636\u0648\u0626\u064a \u0644\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062d\u0633\u0627\u0633\u0629 \u0644\u0644\u0636\u0648\u0621 \u0645\u062b\u0644 \u0627\u0644\u0646\u064a\u0641\u064a\u062f\u064a\u0628\u064a\u0646 \u0648\u0627\u0644\u0641\u0648\u0631\u0648\u0633\u064a\u0645\u064a\u062f \u0648\u0628\u0639\u0636 \u0627\u0644\u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u062d\u064a\u0648\u064a\u0629<\/li>\n<li>\u0628\u064a\u0627\u0636 \u0648\u0642\u0648\u0629 \u062a\u0644\u0648\u064a\u0646 \u0645\u062a\u0646\u0627\u0633\u0642\u0629 \u0645\u0646 \u062f\u0641\u0639\u0629 \u0625\u0644\u0649 \u0623\u062e\u0631\u0649 (\u062a\u0642\u0627\u0633 \u0628\u0642\u064a\u0645 \u0627\u0644\u0645\u062e\u062a\u0628\u0631*)<\/li>\n<li>\u062a\u0648\u0627\u0641\u0642 \u0645\u0645\u062a\u0627\u0632 \u0645\u0639 \u0627\u0644\u0628\u0648\u0644\u064a\u0645\u0631\u0627\u062a \u0627\u0644\u0634\u0627\u0626\u0639\u0629 \u0627\u0644\u0645\u0643\u0648\u0646\u0629 \u0644\u0644\u0623\u063a\u0634\u064a\u0629 \u0645\u062b\u0644 HPMC \u0648PVA \u0648\u0625\u064a\u062b\u064a\u0644 \u0627\u0644\u0633\u0644\u064a\u0644\u0648\u0632<\/li>\n<li>\u062a\u0642\u0644\u064a\u0644 \u0627\u0646\u0633\u062f\u0627\u062f \u0627\u0644\u0641\u0648\u0647\u0629 \u0648\u062a\u062d\u0633\u064a\u0646 \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0627\u0644\u062a\u0639\u0644\u064a\u0642 \u0623\u062b\u0646\u0627\u0621 \u0637\u0644\u0627\u0621 \u0627\u0644\u0631\u0630\u0627\u0630<\/li>\n<\/ul>\n<p dir=\"auto\">\u0648\u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u064a\u0624\u062f\u064a TiO\u2082 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0625\u0644\u0649 \u0639\u064a\u0648\u0628 \u0641\u064a \u0627\u0644\u0637\u0644\u0627\u0621 \u0648\u0639\u062f\u0645 \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u062a\u0639\u062a\u064a\u0645 \u0648\u0645\u062e\u0627\u0637\u0631 \u0631\u0641\u0636 \u0627\u0644\u062f\u064f\u0641\u0639\u0627\u062a \u0628\u0633\u0628\u0628 \u062a\u0648\u0632\u064a\u0639 \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0627\u0644\u0623\u0648\u0633\u0639 \u0646\u0637\u0627\u0642\u064b\u0627 \u0648\u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0645\u0639\u0627\u0644\u062c\u0629 \u0633\u0637\u062d\u064a\u0629 \u0645\u062a\u062e\u0635\u0635\u0629.<\/p>\n<h3 dir=\"auto\"><strong>\u062a\u0639\u062a\u064a\u0645 \u063a\u0644\u0627\u0641 \u0627\u0644\u0643\u0628\u0633\u0648\u0644\u0629 \u0648\u062a\u0639\u0632\u064a\u0632 \u062d\u0627\u062c\u0632 \u0627\u0644\u0631\u0637\u0648\u0628\u0629<\/strong><\/h3>\n<p dir=\"auto\">\u0627\u0644\u062c\u064a\u0644\u0627\u062a\u064a\u0646 \u0627\u0644\u0635\u0644\u0628 \u0648\u0643\u0628\u0633\u0648\u0644\u0627\u062a HPMC \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u0639\u0644\u0649 \u0646\u0637\u0627\u0642 \u0648\u0627\u0633\u0639 <strong>\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong> \u0644\u062d\u0645\u0627\u064a\u0629 \u0645\u0648\u0627\u062f \u0627\u0644\u062a\u0639\u0628\u0626\u0629 \u0627\u0644\u062d\u0633\u0627\u0633\u0629 \u0644\u0644\u0636\u0648\u0621 \u0623\u0648 \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u0645\u0633\u062a\u0631\u0637\u0628\u0629. \u062a\u0645\u0646\u0639 \u0623\u063a\u0644\u0641\u0629 \u0627\u0644\u0643\u0628\u0633\u0648\u0644\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u0634\u0641\u0627\u0641\u0629 \u0628\u0641\u0639\u0627\u0644\u064a\u0629 \u062f\u062e\u0648\u0644 \u0627\u0644\u0631\u0637\u0648\u0628\u0629 \u0648\u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0645\u0643\u0648\u0646\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0627\u0644\u0646\u0634\u0637\u0629 \u0642\u0628\u0644 \u0627\u0644\u0623\u0648\u0627\u0646.<\/p>\n<p dir=\"auto\"><strong>\u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0646\u0645\u0648\u0630\u062c\u064a \u0648\u0627\u0644\u0645\u0632\u0627\u064a\u0627:<\/strong><\/p>\n<ul dir=\"auto\">\n<li>\u062a\u0631\u0643\u064a\u0632 TiO\u2082 \u0641\u064a \u0623\u063a\u0644\u0641\u0629 \u0627\u0644\u0643\u0628\u0633\u0648\u0644\u0627\u062a: 0.5-2.0% \u0628\u0627\u0644\u0648\u0632\u0646\/\u0648\u0632\u0646<\/li>\n<li>\u064a\u062d\u0627\u0641\u0638 \u0639\u0644\u0649 \u0645\u0631\u0648\u0646\u0629 \u0627\u0644\u0643\u0628\u0633\u0648\u0644\u0629 \u0648\u064a\u0645\u0646\u0639 \u0647\u0634\u0627\u0634\u062a\u0647\u0627 \u0623\u062b\u0646\u0627\u0621 \u0627\u0644\u0645\u0646\u0627\u0648\u0644\u0629<\/li>\n<li>\u062a\u062e\u0644\u0642 \u062d\u0627\u062c\u0632\u064b\u0627 \u0645\u0632\u062f\u0648\u062c\u064b\u0627 \u0636\u062f \u0627\u0644\u0636\u0648\u0621 \u0648\u0627\u0644\u0631\u0637\u0648\u0628\u0629\u060c \u0645\u0645\u0627 \u064a\u0637\u064a\u0644 \u0645\u0646 \u0645\u062f\u0629 \u0627\u0644\u0635\u0644\u0627\u062d\u064a\u0629<\/li>\n<li>\u064a\u0636\u0645\u0646 \u0639\u062f\u0645 \u0627\u0644\u062a\u062f\u0627\u062e\u0644 \u0645\u0639 \u0625\u0637\u0644\u0627\u0642 \u0627\u0644\u062f\u0648\u0627\u0621 \u0648\u0627\u0644\u062a\u0648\u0627\u0641\u0631 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a (\u062a\u0645 \u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0630\u0644\u0643 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0630\u0648\u0628\u0627\u0646 USP )<\/li>\n<\/ul>\n<p dir=\"auto\"><strong>\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629<\/strong>\u2019\u062a\u0642\u0644\u0644 \u0643\u064a\u0645\u064a\u0627\u0621 \u0627\u0644\u0633\u0637\u062d \u0627\u0644\u062e\u0627\u0645\u0644\u0629 \u0645\u0646 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0645\u0639 \u0627\u0644\u062c\u064a\u0644\u0627\u062a\u064a\u0646 \u0623\u0648 HPMC\u060c \u0639\u0644\u0649 \u0639\u0643\u0633 \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0627\u0644\u062a\u064a \u0642\u062f \u062a\u063a\u064a\u0631 \u062d\u0631\u0643\u064a\u0629 \u0627\u0644\u062a\u0631\u0637\u064a\u0628 \u0648\u0645\u0644\u0627\u0645\u062d \u0627\u0644\u0630\u0648\u0628\u0627\u0646.<\/p>\n<hr \/>\n<h2>\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u0643\u0627\u0644\u064a\u0641 \u0648\u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0648\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0627\u0644\u0634\u0631\u0627\u0621<\/h2>\n<h3>\u062a\u0628\u0631\u064a\u0631 \u0639\u0644\u0627\u0648\u0629 \u0627\u0644\u0633\u0639\u0631: \u0627\u0644\u0645\u0648\u0627\u0632\u0646\u0629 \u0628\u064a\u0646 \u062a\u062e\u0641\u064a\u0641 \u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0648\u0627\u0644\u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0645\u0627\u062f\u064a\u0629<\/h3>\n<p>\u0648\u0639\u0627\u062f\u0629\u064b \u0645\u0627 \u064a\u062d\u0645\u0644 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0639\u0644\u0627\u0648\u0629 \u0633\u0639\u0631\u064a\u0629 \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 30 \u064850% \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u0628\u062f\u0627\u0626\u0644 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u0639\u0643\u0633 \u0627\u0644\u062a\u0643\u0627\u0644\u064a\u0641 \u0627\u0644\u0625\u0636\u0627\u0641\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u0623\u0643\u062b\u0631 \u0635\u0631\u0627\u0645\u0629\u060c \u0648\u0627\u0644\u062a\u0648\u062b\u064a\u0642 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u060c \u0648\u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0644\u0644\u062f\u0633\u062a\u0648\u0631 \u0627\u0644\u062f\u0648\u0627\u0626\u064a. \u0641\u064a \u062a\u0637\u0628\u064a\u0642 \u0637\u0644\u0627\u0621 \u0627\u0644\u0623\u0642\u0631\u0627\u0635 \u0627\u0644\u0642\u064a\u0627\u0633\u064a \u0627\u0644\u0630\u064a \u064a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 2-3% TiO\u2082 TiO\u2082 \u0641\u064a \u0645\u0639\u0644\u0642 \u0627\u0644\u0637\u0644\u0627\u0621\u060c \u062a\u0636\u064a\u0641 \u0647\u0630\u0647 \u0627\u0644\u0639\u0644\u0627\u0648\u0629 \u0628\u0634\u0643\u0644 \u0639\u0627\u0645 $0.002-0.005 \u0641\u0642\u0637 \u0644\u0643\u0644 \u0648\u062d\u062f\u0629 \u062c\u0631\u0639\u0629 - \u0648\u0647\u064a \u062a\u0643\u0644\u0641\u0629 \u0625\u0636\u0627\u0641\u064a\u0629 \u0639\u0646\u062f \u0645\u0642\u0627\u0631\u0646\u062a\u0647\u0627 \u0628\u0627\u0644\u0639\u0648\u0627\u0642\u0628 \u0627\u0644\u0645\u0627\u0644\u064a\u0629 \u0627\u0644\u0645\u062a\u0631\u062a\u0628\u0629 \u0639\u0644\u0649 \u0627\u0644\u0627\u0646\u062a\u0643\u0627\u0633\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0623\u0648 \u0633\u062d\u0628 \u0627\u0644\u0645\u0646\u062a\u062c.<\/p>\n<p>\u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u062a\u062c\u0627\u0648\u0632 \u0627\u0644\u0631\u0641\u0636 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a \u0623\u062b\u0646\u0627\u0621 \u0645\u0631\u0627\u062c\u0639\u0629 \u0637\u0644\u0628 \u0627\u0644\u062f\u0648\u0627\u0621 \u0628\u0633\u0647\u0648\u0644\u0629 $500,000 \u0628\u0633\u0647\u0648\u0644\u0629 \u0628\u0645\u062c\u0631\u062f \u0627\u0644\u0646\u0638\u0631 \u0641\u064a \u062a\u0643\u0627\u0644\u064a\u0641 \u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u0642\u062f\u064a\u0645 \u0648\u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062a\u0643\u0645\u064a\u0644\u064a\u0629 \u0648\u062a\u0623\u062e\u0631 \u062f\u062e\u0648\u0644 \u0627\u0644\u0633\u0648\u0642. \u0648\u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u064a\u0624\u062f\u064a \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0633\u0648\u0627\u063a\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629 \u0625\u0644\u0649 \u062a\u062f\u0642\u064a\u0642 \u062a\u0646\u0638\u064a\u0645\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0645\u062f\u062f \u0627\u0644\u062c\u062f\u0627\u0648\u0644 \u0627\u0644\u0632\u0645\u0646\u064a\u0629 \u0644\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0644\u0645\u062f\u0629 \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 6 \u064812 \u0634\u0647\u0631\u064b\u0627\u060c \u0645\u0645\u0627 \u064a\u0642\u0644\u0644 \u0645\u0646 \u0627\u0644\u0639\u0645\u0631 \u0627\u0644\u0641\u0639\u0627\u0644 \u0644\u0628\u0631\u0627\u0621\u0629 \u0627\u0644\u0627\u062e\u062a\u0631\u0627\u0639 \u0648\u064a\u0624\u062e\u0631 \u0627\u0644\u0639\u0648\u0627\u0626\u062f \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629. \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0633\u064a\u0627\u0642\u060c \u064a\u0639\u0645\u0644 TiO\u2082 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0643\u0636\u0645\u0627\u0646\u0629 \u0639\u0645\u0644\u064a\u0629 \u0636\u062f \u0627\u0644\u062a\u0639\u0631\u0636 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a \u0627\u0644\u0646\u0647\u0627\u0626\u064a.<\/p>\n<p>\u062a\u0633\u0644\u0637 \u0623\u062d\u062f\u0627\u062b \u0633\u062d\u0628 \u0627\u0644\u0645\u0646\u062a\u062c \u0645\u0632\u064a\u062f\u064b\u0627 \u0645\u0646 \u0627\u0644\u0636\u0648\u0621 \u0639\u0644\u0649 \u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0627\u0644\u0645\u0627\u0644\u064a\u0629. \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u062a\u0633\u0628\u0628 \u062f\u0641\u0639\u0629 \u0648\u0627\u062d\u062f\u0629 \u0645\u0644\u0648\u062b\u0629 \u0645\u0646 TiO\u2082 TiO\u2082 \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0645\u062a\u0639\u062f\u062f\u0629 \u0641\u064a \u062a\u0648\u0644\u064a\u062f \u062a\u0643\u0627\u0644\u064a\u0641 \u0633\u062d\u0628 \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 $10-50 \u0645\u0644\u064a\u0648\u0646\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0633\u062d\u0628 \u0627\u0644\u0645\u0646\u062a\u062c\u060c \u0648\u0627\u0644\u0625\u0628\u0644\u0627\u063a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u060c \u0648\u0627\u0644\u062a\u0648\u0627\u0635\u0644 \u0645\u0639 \u0627\u0644\u0639\u0645\u0644\u0627\u0621\u060c \u0648\u0627\u0644\u0625\u0636\u0631\u0627\u0631 \u0628\u0627\u0644\u0633\u0645\u0639\u0629. \u064a\u062e\u0641\u0641 \u0645\u0648\u0631\u062f\u0648 \u0627\u0644\u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0636\u0648\u0627\u0628\u0637 \u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f\u0629 \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629 \u0648\u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u0627\u0644\u062a\u062a\u0628\u0639 \u0627\u0644\u0643\u0627\u0645\u0644 \u0644\u0644\u062f\u0641\u0639\u0627\u062a.<\/p>\n<p>\u064a\u0644\u0639\u0628 \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0623\u064a\u0636\u064b\u0627 \u062f\u0648\u0631\u064b\u0627 \u062d\u0627\u0633\u0645\u064b\u0627 \u0641\u064a \u0645\u0648\u062b\u0648\u0642\u064a\u0629 \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644. \u064a\u062d\u0627\u0641\u0638 \u0645\u0648\u0631\u062f\u0648 \u0627\u0644\u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0639\u0644\u0649 \u0645\u0648\u0627\u0635\u0641\u0627\u062a \u062e\u0627\u0636\u0639\u0629 \u0644\u0631\u0642\u0627\u0628\u0629 \u0635\u0627\u0631\u0645\u0629 \u0648\u0627\u062a\u0635\u0627\u0644\u0627\u062a \u0645\u0646\u0638\u0645\u0629 \u0644\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u062a\u063a\u064a\u064a\u0631\u060c \u0641\u064a \u062d\u064a\u0646 \u0623\u0646 \u0645\u0648\u0631\u062f\u064a \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0642\u062f \u064a\u0646\u0641\u0630\u0648\u0646 \u062a\u0639\u062f\u064a\u0644\u0627\u062a \u0641\u064a \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u062f\u0648\u0646 \u0625\u062e\u0637\u0627\u0631 \u0643\u0627\u0641\u064d. \u0648\u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u062a\u062a\u062c\u0627\u0648\u0632 \u062a\u0643\u0644\u0641\u0629 \u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0644\u064a\u0646 \u0648\u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0635\u062d\u0629 \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0639\u062f\u0629 \u0633\u0646\u0648\u0627\u062a \u0645\u0646 \u0627\u0644\u0645\u062f\u0641\u0648\u0639\u0627\u062a \u0627\u0644\u0645\u0645\u062a\u0627\u0632\u0629 \u0644\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629.<\/p>\n<h3>\u0642\u0627\u0626\u0645\u0629 \u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0645\u0624\u0647\u0644\u0627\u062a \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0644\u0645\u0634\u062a\u0631\u064a \u0627\u0644\u0623\u062f\u0648\u064a\u0629<\/h3>\n<p>\u064a\u062c\u0628 \u0623\u0646 \u064a\u0628\u062f\u0623 \u062a\u0623\u0647\u064a\u0644 \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0628\u0645\u0631\u0627\u062c\u0639\u0629 \u0645\u0641\u0635\u0644\u0629 \u0644\u0644\u0648\u062b\u0627\u0626\u0642 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629. \u064a\u062c\u0628 \u0623\u0646 \u062a\u062a\u062d\u0642\u0642 \u0641\u0631\u0642 \u0627\u0644\u0645\u0634\u062a\u0631\u064a\u0627\u062a \u0645\u0646 \u062d\u0627\u0644\u0629 \u0645\u0644\u0641 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0627\u0644\u0646\u0634\u0637 (DMF) \u0645\u0639 \u0627\u0644\u0633\u0644\u0637\u0627\u062a \u0627\u0644\u0645\u0639\u0646\u064a\u0629\u060c \u0648\u0627\u0644\u062a\u0623\u0643\u062f \u0645\u0646 \u0634\u0647\u0627\u062f\u0627\u062a \u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u060c \u0648\u062a\u0642\u064a\u064a\u0645 \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u0641\u062a\u064a\u0634 \u0627\u0644\u0623\u062e\u064a\u0631\u0629. \u0648\u064a\u062a\u0637\u0644\u0628 \u0627\u0644\u0645\u0648\u0631\u062f\u0648\u0646 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0648\u0646 \u0628\u0645\u0644\u0627\u062d\u0638\u0627\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0646\u0645\u0648\u0630\u062c 483 \u0623\u0648 \u062e\u0637\u0627\u0628\u0627\u062a \u0627\u0644\u062a\u062d\u0630\u064a\u0631 \u0628\u0630\u0644 \u0627\u0644\u0639\u0646\u0627\u064a\u0629 \u0627\u0644\u0648\u0627\u062c\u0628\u0629 \u0627\u0644\u0645\u0639\u0632\u0632\u0629 \u0642\u0628\u0644 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629.<\/p>\n<p>\u062a\u0648\u0641\u0631 \u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062a\u062f\u0642\u064a\u0642 \u0641\u064a \u0627\u0644\u0645\u0648\u0642\u0639 \u0646\u0638\u0631\u0629 \u062b\u0627\u0642\u0628\u0629 \u0645\u0628\u0627\u0634\u0631\u0629 \u0639\u0644\u0649 \u0636\u0648\u0627\u0628\u0637 \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0648\u0645\u062a\u0627\u0646\u0629 \u0646\u0638\u0627\u0645 \u0627\u0644\u062c\u0648\u062f\u0629. \u064a\u062c\u0628 \u0623\u0646 \u064a\u063a\u0637\u064a \u0646\u0637\u0627\u0642 \u0627\u0644\u062a\u062f\u0642\u064a\u0642 \u062a\u0623\u0647\u064a\u0644 \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u062e\u0627\u0645\u060c \u0648\u0627\u0644\u0636\u0648\u0627\u0628\u0637 \u062f\u0627\u062e\u0644 \u0627\u0644\u0639\u0645\u0644\u064a\u0629\u060c \u0648\u0627\u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u0628\u064a\u0626\u064a\u0629\u060c \u0648\u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0635\u062d\u0629 \u0627\u0644\u062a\u0646\u0638\u064a\u0641\u060c \u0648\u0625\u062c\u0631\u0627\u0621\u0627\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641. \u0648\u064a\u0646\u0628\u063a\u064a \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0628\u0634\u0643\u0644 \u062e\u0627\u0635 \u0639\u0644\u0649 \u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a\u060c \u0648\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u0633\u0637\u062d\u064a\u0629\u060c \u0648\u0642\u062f\u0631\u0627\u062a \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0629.<\/p>\n<p>\u062a\u062d\u062f\u062f \u0627\u062a\u0641\u0627\u0642\u064a\u0627\u062a \u0627\u0644\u062c\u0648\u062f\u0629 \u062a\u0648\u0642\u0639\u0627\u062a \u0648\u0627\u0636\u062d\u0629 \u0641\u064a\u0645\u0627 \u064a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0648\u0627\u0644\u0623\u0633\u0627\u0644\u064a\u0628 \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a\u0629 \u0648\u0627\u0644\u062c\u062f\u0627\u0648\u0644 \u0627\u0644\u0632\u0645\u0646\u064a\u0629 \u0644\u0644\u0625\u062e\u0637\u0627\u0631 \u0628\u0627\u0644\u062a\u063a\u064a\u064a\u0631 \u0648\u0625\u062c\u0631\u0627\u0621\u0627\u062a \u062d\u0644 \u0627\u0644\u0634\u0643\u0627\u0648\u0649. \u064a\u062c\u0628 \u0623\u0646 \u062a\u062d\u062f\u062f \u0647\u0630\u0647 \u0627\u0644\u0627\u062a\u0641\u0627\u0642\u0627\u062a \u0646\u0637\u0627\u0642\u0627\u062a \u0627\u0644\u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0627\u0644\u0645\u0642\u0628\u0648\u0644\u0629\u060c \u0648\u062a\u062a\u0637\u0644\u0628 \u0625\u062e\u0637\u0627\u0631\u064b\u0627 \u0645\u0633\u0628\u0642\u064b\u0627 - \u0639\u0627\u062f\u0629\u064b \u0645\u0627 \u064a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 90 \u0648180 \u064a\u0648\u0645\u064b\u0627 - \u0644\u0625\u062c\u0631\u0627\u0621 \u062a\u0639\u062f\u064a\u0644\u0627\u062a \u0639\u0644\u0649 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a\u060c \u0648\u062a\u062d\u062f\u062f \u0628\u0631\u0648\u062a\u0648\u0643\u0648\u0644\u0627\u062a \u0627\u0644\u062a\u0635\u0639\u064a\u062f \u0641\u064a \u062d\u0627\u0644\u0629 \u062d\u062f\u0648\u062b \u062d\u0627\u0644\u0627\u062a \u0639\u062f\u0645 \u0645\u0637\u0627\u0628\u0642\u0629 \u0627\u0644\u0645\u0648\u0627\u0635\u0641\u0627\u062a.<\/p>\n<p>\u062a\u0633\u0627\u0639\u062f \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0627\u062a \u0627\u0644\u062a\u0648\u0631\u064a\u062f \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u0639\u0644\u0649 \u062a\u0642\u0644\u064a\u0644 \u0636\u0639\u0641 \u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062a\u0648\u0631\u064a\u062f \u0645\u0639 \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062c\u0648\u062f\u0629. \u064a\u062a\u0637\u0644\u0628 \u062a\u0623\u0647\u064a\u0644 \u0627\u062b\u0646\u064a\u0646 \u0645\u0646 \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0644\u0645\u0648\u0627\u0635\u0641\u0627\u062a TiO\u2082 \u0645\u062a\u0643\u0627\u0641\u0626\u0629 \u0627\u062e\u062a\u0628\u0627\u0631\u064b\u0627 \u0645\u0642\u0627\u0631\u0646\u064b\u0627 \u0644\u062a\u0623\u0643\u064a\u062f \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u0645\u0648\u0627\u062f \u0648\u0642\u062f \u064a\u0646\u0637\u0648\u064a \u0639\u0644\u0649 \u0625\u062e\u0637\u0627\u0631 \u062a\u0646\u0638\u064a\u0645\u064a \u0627\u0639\u062a\u0645\u0627\u062f\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u062a\u0632\u0627\u0645\u0627\u062a \u0627\u0644\u0625\u064a\u062f\u0627\u0639. \u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u0627\u0644\u062a\u0648\u0631\u064a\u062f \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u064a\u0633\u062a\u0647\u0644\u0643 \u0627\u0644\u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0645\u0648\u0627\u0631\u062f\u060c \u0625\u0644\u0627 \u0623\u0646\u0647 \u064a\u0648\u0641\u0631 \u062d\u0645\u0627\u064a\u0629 \u062d\u0627\u0633\u0645\u0629 \u0623\u062b\u0646\u0627\u0621 \u0627\u0646\u0642\u0637\u0627\u0639 \u0627\u0644\u062a\u0648\u0631\u064a\u062f \u0623\u0648 \u0627\u0644\u0623\u062d\u062f\u0627\u062b \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u062c\u0648\u062f\u0629.<\/p>\n<p>\u062a\u062e\u0637\u064a\u0637 \u0627\u0644\u0645\u0647\u0644\u0629 \u0627\u0644\u0632\u0645\u0646\u064a\u0629 \u0645\u0647\u0645 \u0628\u0646\u0641\u0633 \u0627\u0644\u0642\u062f\u0631 \u0644\u0627\u0633\u062a\u0645\u0631\u0627\u0631\u064a\u0629 \u0627\u0644\u0625\u0646\u062a\u0627\u062c. \u0641\u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u064a\u062a\u0637\u0644\u0628 TiO\u2082 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0646 8 \u0625\u0644\u0649 12 \u0623\u0633\u0628\u0648\u0639\u064b\u0627 \u0628\u0633\u0628\u0628 \u0627\u062e\u062a\u0628\u0627\u0631 \u0625\u0637\u0644\u0627\u0642 \u0627\u0644\u062f\u0641\u0639\u0627\u062a \u0648\u0625\u0639\u062f\u0627\u062f \u0627\u0644\u0648\u062b\u0627\u0626\u0642\u060c \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0640 2-4 \u0623\u0633\u0627\u0628\u064a\u0639 \u0644\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629. \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0633\u0627\u0639\u062f \u0627\u0644\u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u0625\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0644\u0644\u0645\u062e\u0632\u0648\u0646 \u0648\u0628\u0631\u0627\u0645\u062c \u0627\u0644\u0645\u062e\u0632\u0648\u0646 \u0627\u0644\u062a\u064a \u064a\u062f\u064a\u0631\u0647\u0627 \u0627\u0644\u0628\u0627\u0626\u0639\u0648\u0646 \u0641\u064a \u062a\u0639\u0648\u064a\u0636 \u0647\u0630\u0627 \u0627\u0644\u062a\u0639\u0631\u0636 \u0644\u0644\u0645\u0647\u0644\u0629 \u0627\u0644\u0632\u0645\u0646\u064a\u0629 \u0627\u0644\u0645\u0645\u062a\u062f\u0629.<\/p>\n<hr \/>\n<h2>\u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u0627\u0644\u0634\u0627\u0626\u0639\u0629<\/h2>\n<h3>1. \u0645\u0627 \u0647\u064a \u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641\u0627\u062a \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0628\u064a\u0646 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0648\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0642\u0628\u0648\u0644 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u061f<\/h3>\n<p>\u064a\u062a\u0648\u0627\u0641\u0642 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0639 \u0645\u062a\u0637\u0644\u0628\u0627\u062a USP \u0648 EP \u0648 JP monograph\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u062d\u062f\u0648\u062f \u0627\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u0623\u0648\u0644\u064a\u0629 \u0627\u0644\u0635\u0627\u0631\u0645\u0629\u060c \u0648\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u062a\u0641\u0635\u064a\u0644\u064a\u0629\u060c \u0648\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062a\u0635\u0646\u064a\u0639 GMP. \u0648\u064a\u062a\u0648\u0627\u0641\u0642 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0645\u0639 \u0644\u0648\u0627\u0626\u062d \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0644\u0644\u0645\u0636\u0627\u0641\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0628\u0645\u0648\u062c\u0628 21 CFR 73.575\u060c \u0648\u0644\u0643\u0646\u0647 \u064a\u0641\u062a\u0642\u0631 \u0625\u0644\u0649 \u0639\u0645\u0642 \u0627\u0644\u062a\u0648\u062b\u064a\u0642 \u0648\u0636\u0648\u0627\u0628\u0637 \u0627\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u0645\u0637\u0644\u0648\u0628\u0629 \u0644\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629. \u0648\u062a\u062a\u0648\u0642\u0639 \u0627\u0644\u0648\u0643\u0627\u0644\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0639\u0645\u0648\u0645\u064b\u0627 \u0627\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0633\u0648\u0627\u063a\u0627\u062a \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0644\u0636\u0645\u0627\u0646 \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u0645\u0646\u062a\u062c \u0648\u0633\u0644\u0627\u0645\u062a\u0647 \u0648\u062c\u0627\u0647\u0632\u064a\u062a\u0647 \u0644\u0644\u0645\u0648\u0627\u0641\u0642\u0629.<\/p>\n<h3>2. \u0643\u064a\u0641 \u064a\u0624\u062b\u0631 \u062a\u0648\u0632\u064a\u0639 \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0639\u0644\u0649 \u0623\u062f\u0627\u0621 \u0637\u0644\u0627\u0621 \u0627\u0644\u0623\u0642\u0631\u0627\u0635\u061f<\/h3>\n<p>\u064a\u062a\u064a\u062d \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u0645\u0636\u0628\u0648\u0637 \u0644\u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u0627\u0644\u062a\u0634\u062a\u062a \u0627\u0644\u0645\u0646\u062a\u0638\u0645 \u062f\u0627\u062e\u0644 \u0645\u0639\u0644\u0642\u0627\u062a \u0627\u0644\u0637\u0644\u0627\u0621\u060c \u0645\u0645\u0627 \u064a\u0642\u0644\u0644 \u0645\u0646 \u0627\u0644\u062a\u0643\u062a\u0644 \u0648\u0627\u0644\u062a\u0631\u0633\u064a\u0628 \u0627\u0644\u0630\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0639\u064a\u0648\u0628 \u0627\u0644\u0637\u0644\u0627\u0621. \u062a\u062f\u0639\u0645 \u0627\u0644\u062a\u0648\u0632\u064a\u0639\u0627\u062a \u0627\u0644\u0636\u064a\u0642\u0629 \u0633\u0645\u0643 \u063a\u0634\u0627\u0621 \u0645\u062a\u0646\u0627\u0633\u0642 \u0648\u0639\u062a\u0627\u0645\u0629 \u0645\u062d\u0633\u0651\u0646\u0629 \u0648\u062d\u0645\u0627\u064a\u0629 \u0645\u0648\u062b\u0648\u0642\u0629 \u0644\u0648\u0627\u062c\u0647\u0627\u062a \u0628\u0631\u0645\u062c\u0629 \u0627\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u062d\u0633\u0627\u0633\u0629 \u0644\u0644\u0636\u0648\u0621. \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0624\u062b\u0631 \u0627\u0644\u062a\u0628\u0627\u064a\u0646 \u0641\u064a \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0633\u0644\u0628\u064b\u0627 \u0639\u0644\u0649 \u0633\u0644\u0648\u0643 \u0627\u0644\u0631\u0630\u0627\u0630\u060c \u0648\u0633\u0644\u0627\u0633\u0629 \u0627\u0644\u0637\u0644\u0627\u0621\u060c \u0648\u0641\u064a \u0627\u0644\u0646\u0647\u0627\u064a\u0629 \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u0630\u0648\u0628\u0627\u0646 \u0639\u0628\u0631 \u062f\u0641\u0639\u0627\u062a \u0627\u0644\u0625\u0646\u062a\u0627\u062c.<\/p>\n<h3>3. \u0645\u0627 \u0647\u064a \u0627\u0644\u0648\u062b\u0627\u0626\u0642 \u0627\u0644\u062a\u064a \u064a\u0646\u0628\u063a\u064a \u0623\u0646 \u062a\u0637\u0644\u0628\u0647\u0627 \u0641\u0631\u0642 \u0627\u0644\u0645\u0634\u062a\u0631\u064a\u0627\u062a \u0644\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0644\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u0633\u0644\u064a\u0645\u0629 \u0628\u064a\u0626\u064a\u0627\u064b\/\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u0633\u0644\u064a\u0645\u0629 \u0628\u064a\u0626\u064a\u0627\u064b\u061f<\/h3>\n<p>\u064a\u062c\u0628 \u0623\u0646 \u062a\u0637\u0644\u0628 \u0641\u0631\u0642 \u0627\u0644\u0645\u0634\u062a\u0631\u064a\u0627\u062a \u0634\u0647\u0627\u062f\u0627\u062a \u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0627\u0644\u062f\u064f\u0641\u0639\u0627\u062a (CoAs)\u060c \u0648\u062e\u0637\u0627\u0628\u0627\u062a \u062a\u0641\u0648\u064a\u0636 DMF \u0627\u0644\u0646\u0634\u0637\u0629\u060c \u0648\u0634\u0647\u0627\u062f\u0627\u062a \u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u060c \u0648\u0633\u062c\u0644\u0627\u062a \u0627\u0644\u062a\u0641\u062a\u064a\u0634 \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f\u0629. \u064a\u062c\u0628 \u0623\u0646 \u062a\u062a\u0636\u0645\u0646 \u0627\u0644\u0648\u062b\u0627\u0626\u0642 \u0627\u0644\u0625\u0636\u0627\u0641\u064a\u0629 \u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062b\u0628\u0627\u062a\u060c \u0648\u0625\u0642\u0631\u0627\u0631\u0627\u062a \u0645\u0631\u0636 \u062c\u0646\u0648\u0646 \u0627\u0644\u0628\u0642\u0631\/\u0627\u0644\u062a\u0633\u0645\u0645 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0627\u0644\u062a\u0627\u062c\u064a\/\u0627\u0644\u062a\u0633\u0645\u0645 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0627\u0644\u0645\u062a\u0639\u062f\u062f \u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646\u060c \u0648\u0628\u064a\u0627\u0646\u0627\u062a \u0645\u0633\u0628\u0628\u0627\u062a \u0627\u0644\u062d\u0633\u0627\u0633\u064a\u0629\u060c \u0648\u0627\u062a\u0641\u0627\u0642\u064a\u0627\u062a \u0627\u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u062a\u064a \u062a\u062d\u062f\u062f \u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u062a\u063a\u064a\u064a\u0631. \u062a\u0639\u062a\u0628\u0631 \u0645\u0644\u062e\u0635\u0627\u062a \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u0633\u0646\u0648\u064a\u0629 \u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u0645\u0646\u062a\u062c \u0630\u0627\u062a \u0642\u064a\u0645\u0629 \u0623\u064a\u0636\u064b\u0627 \u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u062a\u0633\u0627\u0642 \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644.<\/p>\n<hr \/>\n<h2>\u0627\u0644\u062e\u0644\u0627\u0635\u0629<\/h2>\n<p>\u064a\u0648\u0641\u0631 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0632\u0627\u064a\u0627 \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u0642\u064a\u0627\u0633 \u0641\u064a \u0627\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u0646\u0642\u0627\u0621 \u0648\u0627\u0644\u062b\u0642\u0629 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0648\u0623\u062f\u0627\u0621 \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0628\u0631\u0631 \u062a\u0643\u0644\u0641\u062a\u0647 \u0627\u0644\u0623\u0639\u0644\u0649 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u062f\u0631\u062c\u0627\u062a \u0627\u0644\u0642\u064a\u0627\u0633\u064a\u0629. \u0648\u062a\u0642\u0644\u0644 \u062d\u062f\u0648\u062f \u0627\u0644\u0634\u0648\u0627\u0626\u0628 \u0627\u0644\u0635\u0627\u0631\u0645\u0629 \u0648\u062a\u0648\u0632\u064a\u0639 \u062d\u062c\u0645 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0627\u0644\u062e\u0627\u0636\u0639 \u0644\u0644\u0631\u0642\u0627\u0628\u0629 \u0648\u0636\u0648\u0627\u0628\u0637 \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0641\u064a \u0645\u0645\u0627\u0631\u0633\u0627\u062a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u062c\u064a\u062f\u0629 \u0645\u0646 \u0645\u062e\u0627\u0637\u0631 \u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0645\u0639 \u062f\u0639\u0645 \u062c\u0648\u062f\u0629 \u0627\u0644\u0645\u0646\u062a\u062c \u0627\u0644\u0645\u062a\u0646\u0627\u0633\u0642\u0629 \u0639\u0628\u0631 \u0627\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0627\u0644\u0645\u062a\u0646\u0648\u0639\u0629.<\/p>\n<p>\u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0645\u0635\u0646\u0639\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u064a\u0631\u0643\u0632\u0648\u0646 \u0639\u0644\u0649 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u0629 \u0648\u0627\u0644\u0625\u0646\u062a\u0627\u062c \u0627\u0644\u062a\u062c\u0627\u0631\u064a \u0627\u0644\u0645\u0648\u062b\u0648\u0642 \u0628\u0647\u060c \u064a\u0633\u0627\u0639\u062f TiO\u2082 \u0627\u0644\u0645\u062a\u0648\u0627\u0641\u0642 \u0645\u0639 \u0627\u0644\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629 \u0639\u0644\u0649 \u062a\u062c\u0646\u0628 \u0627\u0644\u062a\u0643\u0627\u0644\u064a\u0641 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0641\u0634\u0644 \u0627\u0644\u062f\u0641\u0639\u0627\u062a \u0648\u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u0631\u0643\u064a\u0628 \u0648\u0627\u0646\u0642\u0637\u0627\u0639 \u0627\u0644\u0625\u0645\u062f\u0627\u062f. \u0643\u0645\u0627 \u062a\u0639\u0632\u0632 \u0634\u0631\u0627\u0643\u0627\u062a \u0627\u0644\u0645\u0648\u0631\u062f\u064a\u0646 \u0627\u0644\u0642\u0648\u064a\u0629 \u0627\u0644\u0645\u062f\u0639\u0648\u0645\u0629 \u0628\u0628\u0631\u0648\u062a\u0648\u0643\u0648\u0644\u0627\u062a \u0627\u0644\u062a\u0623\u0647\u064a\u0644 \u0627\u0644\u0642\u0648\u064a\u0629 \u0648\u062e\u0637\u0637 \u0627\u0644\u062a\u0648\u0631\u064a\u062f \u0627\u0644\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0645\u0631\u0648\u0646\u0629 \u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062a\u0648\u0631\u064a\u062f.<\/p>\n<p>\u0645\u0639 \u0627\u0633\u062a\u0645\u0631\u0627\u0631 \u062a\u0643\u062b\u064a\u0641 \u0627\u0644\u062a\u062f\u0642\u064a\u0642 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a \u0627\u0644\u0639\u0627\u0644\u0645\u064a \u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u0633\u0648\u0627\u063a\u0627\u062a \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0639\u0627\u0644\u0645\u060c \u064a\u0638\u0644 \u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0627\u0644\u062e\u064a\u0627\u0631 \u0627\u0644\u0623\u0643\u062b\u0631 \u0642\u0627\u0628\u0644\u064a\u0629 \u0644\u0644\u062f\u0641\u0627\u0639 \u0639\u0646\u0647 \u0648\u0627\u0644\u0623\u0643\u062b\u0631 \u0633\u0644\u0627\u0645\u0629 \u0645\u0646 \u0627\u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629 \u0644\u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0630\u0627\u062a \u0627\u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u062d\u0631\u062c\u0629.<\/p>","protected":false},"excerpt":{"rendered":"<p>\u062a\u0628\u062d\u062b \u0647\u0630\u0647 \u0627\u0644\u0645\u0642\u0627\u0644\u0629 \u0641\u064a \u0627\u0644\u0645\u0632\u0627\u064a\u0627 \u0627\u0644\u062a\u0642\u0646\u064a\u0629 \u0648\u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0648\u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629 \u0627\u0644\u0647\u0627\u0645\u0629 \u0644\u062b\u0627\u0646\u064a \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u064a\u062a\u0627\u0646\u064a\u0648\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u062f\u0631\u062c\u0627\u062a \u0627\u0644\u0642\u064a\u0627\u0633\u064a\u0629\u060c \u0645\u0639 \u062a\u0633\u0644\u064a\u0637 \u0627\u0644\u0636\u0648\u0621 \u0639\u0644\u0649 \u062f\u0648\u0631\u0647 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0641\u064a \u0636\u0645\u0627\u0646 \u0627\u0644\u0627\u0645\u062a\u062b\u0627\u0644 \u0648\u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0648\u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0627\u0644\u062a\u0631\u0643\u064a\u0628.<\/p>","protected":false},"author":1,"featured_media":917,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[171,118,169,170,172],"class_list":["post-916","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news","tag-pharmaceutical-excipient-purity","tag-pharmaceutical-grade-titanium-dioxide","tag-pharmaceutical-vs-food-grade-titanium-dioxide","tag-titanium-dioxide-excipient","tag-titanium-dioxide-for-drug-formulation"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/posts\/916","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/comments?post=916"}],"version-history":[{"count":0,"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/posts\/916\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/media\/917"}],"wp:attachment":[{"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/media?parent=916"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/categories?post=916"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ar\/wp-json\/wp\/v2\/tags?post=916"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}