{"id":888,"date":"2026-04-29T17:20:54","date_gmt":"2026-04-29T09:20:54","guid":{"rendered":"https:\/\/www.hushentitanium.com\/?p=888"},"modified":"2026-04-29T17:20:54","modified_gmt":"2026-04-29T09:20:54","slug":"why-pharmaceutical-grade-titanium-dioxide-is-used-in-tablet-and-capsule-formulations","status":"publish","type":"post","link":"https:\/\/www.hushentitanium.com\/ko\/why-pharmaceutical-grade-titanium-dioxide-is-used-in-tablet-and-capsule-formulations\/","title":{"rendered":"\uc815\uc81c \ubc0f \ucea1\uc290 \uc81c\ud615\uc5d0 \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc774 \uc0ac\uc6a9\ub418\ub294 \uc774\uc720"},"content":{"rendered":"
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\uc18c\uac1c<\/h2>\n

\ud770\uc0c9 \uc815\uc81c\ub098 \ucea1\uc290\uc744 \ubcf5\uc6a9\ud574 \ubcf8 \uc801\uc774 \uc788\ub2e4\uba74 \ub2e4\uc74c\uacfc \uac19\uc740 \uacbd\ud5d8\uc744 \ud574\ubcf4\uc168\uc744 \uac83\uc785\ub2c8\ub2e4. \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284<\/strong><\/a><\/span>, \ub294 \uacbd\uad6c\uc6a9 \uace0\ud615 \uc81c\ud615\uc5d0\uc11c \uac00\uc7a5 \ub110\ub9ac \uc0ac\uc6a9\ub418\ub294 \ubd80\ud615\uc81c \uc911 \ud558\ub098\uc785\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uc815\uc81c \ucf54\ud305 \ubc0f \ucea1\uc290 \uaecd\uc9c8\uc5d0 \ubd88\ud22c\uba85\ub3c4, \uc0c9\uc0c1 \uc77c\uad00\uc131 \ubc0f \uad11\uc548\uc815\uc131\uc744 \uc81c\uacf5\ud558\uae30 \uc704\ud574 \uc0ac\uc6a9\ub429\ub2c8\ub2e4.<\/p>\n

\uc774 \uac00\uc774\ub4dc\ub294 \uc758\uc57d\ud488 \uc81c\ud615\uc5d0 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc744 \uc0ac\uc6a9\ud558\ub294 \uc774\uc720, \uc758\uc57d\ud488\uc5d0\uc11c \uc548\uc804\ud55c\uc9c0 \uc5ec\ubd80, \ub300\uccb4 \uac00\ub2a5\ud55c \uc7ac\ub8cc\ub294 \ubb34\uc5c7\uc778\uc9c0, \uc5b4\ub5a4 \uc751\uc6a9 \ubd84\uc57c\uc5d0\uc11c \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284 \uc0ac\uc6a9\uc774 \uc5ec\uc804\ud788 \ud544\uc218\uc801\uc778\uc9c0 \ub4f1 \uc870\uc81c\uc790, \uc870\ub2ec \ud300 \ubc0f \ud488\uc9c8 \uc804\ubb38\uac00\uac00 \ud754\ud788 \ubb3b\ub294 \uc8fc\uc694 \uc9c8\ubb38\uc5d0 \ub300\ud574 \uc124\uba85\ud569\ub2c8\ub2e4.<\/p>\n

\uc815\uc81c\uc5d0 \uc81c\uc57d \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc774 \uc0ac\uc6a9\ub418\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc778\uac00\uc694?<\/h2>\n

\uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284(TiO\u2082, CAS 13463-67-7)\uc740 \uc815\uc81c \uc81c\uc870\uc5d0\uc11c \uc5ec\ub7ec \uac00\uc9c0 \ud544\uc218 \uae30\ub2a5\uc744 \uc218\ud589\ud558\ub294 \uace0\uc21c\ub3c4 \ubc31\uc0c9 \ubd84\ub9d0\uc785\ub2c8\ub2e4. \uac00\uc7a5 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \uc138\ubd84\ud654\ud574 \ubcf4\uaca0\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubd88\ud22c\uba85\ub3c4 - \ud0dc\ube14\ub9bf \ucf54\uc5b4 \uc228\uae30\uae30<\/h3>\n

\ub9ce\uc740 \ud65c\uc131 \uc81c\uc57d \uc131\ubd84(API)\uc740 \ubbf8\uc0c9, \ud669\uac08\uc0c9, \uac08\uc0c9, \uc2ec\uc9c0\uc5b4 \uc5bc\ub8e9\ub35c\ub8e9\ud55c \uc0c9\uc744 \ub760\ub294 \ub4f1 \ub9e4\ub825\uc801\uc774\uc9c0 \uc54a\uc740 \uc0c9\uc744 \ub760\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud658\uc790\uac00 \ud575\uc2ec\uc744 \ubcfc \uc218 \uc788\ub2e4\uba74 \uc81c\ud488\uc774 \ub9e4\ub825\uc801\uc73c\ub85c \ubcf4\uc774\uc9c0 \uc54a\uc744 \uac83\uc785\ub2c8\ub2e4. \uc81c\uc57d \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uac00\uc2dc\uad11\uc120\uacfc \uc790\uc678\uc120\uc744 \ubaa8\ub450 \ubd84\uc0b0\uc2dc\ucf1c \ucf54\uc5b4\ub97c \uc644\uc804\ud788 \uac00\ub9ac\ub294 \uade0\uc77c\ud55c \ud770\uc0c9 \uc7a5\ubcbd\uc744 \ub9cc\ub4ed\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubd88\ud22c\uba85\ub3c4\ub294 \uc815\uc81c \ucf54\ud305\uc5d0\uc11c TiO\u2082\uc758 \uac00\uc7a5 \uc911\uc694\ud55c \uae30\ub2a5\uc785\ub2c8\ub2e4.<\/p>\n

\ud0dc\ube14\ub9bf \ucf54\ud305 \uc5c5\uacc4\uc5d0\uc11c\ub294 \ucd5c\uc801\uc758 \ubd88\ud22c\uba85\ub3c4\uc640 \uad11\ud0dd\uc744 \uad6c\ud604\ud558\uae30 \uc704\ud55c \ud45c\uc900 \ubc31\uc0c9 \uc548\ub8cc\ub85c \uc624\ub7ab\ub3d9\uc548 TiO\u2082\ub97c \uc0ac\uc6a9\ud574 \uc654\uc2b5\ub2c8\ub2e4. \ud0c4\uc0b0\uce7c\uc298\uacfc \uc300 \uc804\ubd84\uacfc \uac19\uc740 \ub300\uccb4 \ubd88\ud22c\uba85\uc81c\uac00 \ud3c9\uac00\ub418\uc5c8\uc9c0\ub9cc \ub3d9\uc77c\ud55c \ub18d\ub3c4\uc5d0\uc11c \ub3d9\uc77c\ud55c \ucee4\ubc84\ub9ac\uc9c0\ub97c \ub2ec\uc131\ud558\ub294 \uac83\uc740 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc790\uc678\uc120 \ucc28\ub2e8 - \uc758\uc57d\ud488 \uc720\ud1b5\uae30\ud55c \uc5f0\uc7a5<\/h3>\n

\ub9ce\uc740 API\ub294 \uad11\uc5d0 \ubbfc\uac10\ud569\ub2c8\ub2e4. \uc57d\uad6d \ucc3d\ubb38\uc774\ub098 \uac00\uc815\uc6a9 \uc870\uba85\uc744 \ud1b5\ud574\uc11c\ub77c\ub3c4 \ube5b\uc5d0 \ub178\ucd9c\ub418\uba74 \uc57d\ud6a8\uac00 \uc800\ud558\ub418\uac70\ub098 \uc720\ud574\ud55c \ubd80\uc0b0\ubb3c\uc774 \uc0dd\uc131\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \ubb3c\ub9ac\uc801 \uc790\uc678\uc120 \ud544\ud130 \uc5ed\ud560\uc744 \ud558\uc5ec \uc790\uc678\uc120\uc774 \uc57d\ud488\uc5d0 \ub3c4\ub2ec\ud558\uae30 \uc804\uc5d0 \ud761\uc218\ud558\uac70\ub098 \ubc18\uc0ac\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uad11\uc548\uc815\uc131\uc740 \uad11\ubcc0\uc131 \uc57d\ubb3c\uc758 \uc720\ud1b5\uae30\ud55c\uc744 \uc5f0\uc7a5\ud558\uace0 \ud658\uc790\uc758 \uc548\uc804\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4.<\/p>\n

\ud658\uc790 \uaddc\uc815 \uc900\uc218 - \ud654\uc774\ud2b8 \ud0dc\ube14\ub9bf \ud45c\uc900<\/h3>\n

\ud658\uc790\ub4e4\uc740 \ud770\uc0c9\uc744 \uccad\uacb0, \ud488\uc9c8, \uc758\uc57d\ud488\uacfc \uc5f0\uad00\uc2dc\ud0b5\ub2c8\ub2e4. \uc218\uc2ed \ub144\uac04\uc758 \uc81c\uc57d \ub9c8\ucf00\ud305\uc744 \ud1b5\ud574 \ud770\uc0c9\uc740 \uacbd\uad6c\uc6a9 \uace0\ud615 \uc81c\ud615\uc758 \uae30\ubcf8 \uc0c9\uc0c1\uc73c\ub85c \uc790\ub9ac \uc7a1\uc558\uc2b5\ub2c8\ub2e4. \ud68c\uc0c9, \ubca0\uc774\uc9c0\uc0c9 \ub610\ub294 \ubc18\ud22c\uba85 \ucea1\uc290\uacfc \uac19\uc740 \ud604\uc800\ud55c \ud3b8\ucc28\ub294 \ud2b9\ud788 \ub178\uc778\uc774\ub098 \ub2e4\uc57d\uc81c \ubcf5\uc6a9 \ud658\uc790\uc758 \uacbd\uc6b0 \ud63c\ub780\uc744 \uc57c\uae30\ud558\uace0 \uc21c\uc751\ub3c4\ub97c \ub5a8\uc5b4\ub728\ub9ac\uac70\ub098 \ud22c\uc57d \uc624\ub958\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\uc57d \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \ud658\uc790\ub4e4\uc774 \uc54c\uc544\ubcf4\uace0 \uc2e0\ub8b0\ud560 \uc218 \uc788\ub294 \ubc1d\uace0 \uc77c\uad00\ub41c \ud770\uc0c9\uc744 \ubcf4\uc7a5\ud569\ub2c8\ub2e4.<\/p>\n

\"Pharmaceutical
\uc758\uc57d\ud488 \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c4<\/figcaption><\/figure>\n

\uc704\uc870 \ubc29\uc9c0 \ubc0f \ube0c\ub79c\ub4dc \uc544\uc774\ub374\ud2f0\ud2f0<\/h3>\n

\ubcf5\uc81c\uac00 \uc5b4\ub824\uc6b4 \uade0\uc77c\ud55c \ud770\uc0c9 \ub9c8\uac10\uc740 \uc18c\uadf9\uc801\uc778 \uc704\uc870 \ubc29\uc9c0 \uc218\ub2e8\uc73c\ub85c \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \uc81c\uc57d \ud68c\uc0ac\ub294 \uace0\uc720\ud55c \ud770\uc0c9 \ub610\ub294 TiO\u2082 \ud568\uc720 \uceec\ub7ec \ucf54\ud305\uc744 \ud1b5\ud574 \uc81c\ud488\uc744 \ube0c\ub79c\ub4dc\ud654\ud558\uace0 \uc815\ud488 \uc758\uc57d\ud488\uacfc \uac00\uc9dc \uc758\uc57d\ud488\uc744 \uad6c\ubd84\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc758\uc57d\ud488\uc6a9 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc758\uc57d\ud488\uc5d0\uc11c \uc548\uc804\ud55c\uac00\uc694?<\/h2>\n

\uc774 \uc9c8\ubb38\uc740 \uc870\uc81c\uc790\uc640 \uaddc\uc81c \ub2f9\uad6d \uc804\ubb38\uac00\ub4e4\uc774 \uac00\uc7a5 \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38\uc785\ub2c8\ub2e4. \uc5b4\ub5a4 \uaddc\uc81c \uae30\uad00\uc5d0 \ubb38\uc758\ud558\ub290\ub0d0\uc5d0 \ub530\ub77c \ub2f5\uc740 \ub2e4\ub974\uc9c0\ub9cc, \uc758\uc57d\ud488\uc758 \uc9c0\uc18d\uc801\uc778 \uc0ac\uc6a9\uc744 \uac15\ub825\ud788 \uc9c0\uc9c0\ud558\ub294 \uc758\uacac\uc774 \uc9c0\ubc30\uc801\uc785\ub2c8\ub2e4.<\/p>\n

\ubbf8\uad6d FDA \uc785\uc7a5 - \uc548\uc804 \ubc0f \uc2b9\uc778<\/h3>\n

\ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA)\uc740 21 CFR 73.1575\uc5d0 \ub530\ub77c \uc758\uc57d\ud488 \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc744 \uc0c9\uc18c \ucca8\uac00\uc81c\ub85c \uaddc\uc81c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. FDA\ub294 \uc758\uc57d\ud488\uc5d0\uc11c \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc758 \uc548\uc804\uc131\uc5d0 \ub300\ud55c \uc6b0\ub824\ub97c \uc5b8\uae09\ud558\uc9c0 \uc54a\uace0 \uc788\uc73c\uba70, \ud2f0\ud0c0\ub284\uc758 \uc591\uc774 \uc81c\ud488 \uc911\ub7c9 \uae30\uc900\uc73c\ub85c 1%\ub97c \ucd08\uacfc\ud558\uc9c0 \uc54a\ub3c4\ub85d \uc694\uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. TiO\u2082\ub294 FDA \ube44\ud65c\uc131 \uc131\ubd84 \ub370\uc774\ud130\ubca0\uc774\uc2a4\uc5d0 \ub530\ub77c \uc548\uc804\ud558\uace0 \uc2b9\uc778\ub41c \ubd80\ud615\uc81c\ub85c \uc778\uc815\ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc758\uc57d\ud488\uc5d0 \ub300\ud55c \uc720\ub7fd \uaddc\uc81c \ud604\ud669 \uc7ac\ud655\uc778<\/h3>\n

2021\ub144 \uc720\ub7fd\uc2dd\ud488\uc548\uc804\uccad(EFSA)\uc740 \ub098\ub178 \ud06c\uae30 \uc785\uc790\uc5d0 \ub300\ud55c \uc720\uc804\ub3c5\uc131 \ub370\uc774\ud130 \uaca9\ucc28\ub85c \uc778\ud574 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc774 \ub354 \uc774\uc0c1 \uc2dd\ud488 \ucca8\uac00\ubb3c(E171)\ub85c\uc11c \uc548\uc804\ud558\uc9c0 \uc54a\ub2e4\uace0 \uacb0\ub860\uc9c0\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub85c \uc778\ud574 EU\ub294 \uc2dd\ud488\uc5d0 E171\uc744 \uae08\uc9c0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uacb0\uc815\uc801\uc73c\ub85c \uc774 \uacb0\uc815\uc740 \uc81c\uc57d \ubd84\uc57c\uc5d0\ub294 \uc801\uc6a9\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/strong> \uc720\ub7fd \uc758\uc57d\ud488\uccad(EMA)\uc5d0\uc11c \ubcc4\ub3c4\uc758 \ud3c9\uac00\ub97c \uc2e4\uc2dc\ud588\uc2b5\ub2c8\ub2e4. 2025\ub144 8\uc6d4 6\uc77c, \uc720\ub7fd\uc704\uc6d0\ud68c\ub294 \uc758\uc57d\ud488\uc5d0 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc744 \uacc4\uc18d \uc0ac\uc6a9\ud574\uc57c \ud55c\ub2e4\ub294 \uc785\uc7a5\uc744 \uc7ac\ud655\uc778\ud588\uc2b5\ub2c8\ub2e4. \uc774 \ubcf4\uace0\uc11c\ub294 \uc758\uc57d\ud488\uc758 \uc548\uc804\uc131, \ud488\uc9c8 \ubc0f \ud6a8\ub2a5\uc5d0 \ub300\ud55c \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc758 \uc911\uc694\uc131, \uc2e4\ud604 \uac00\ub2a5\ud55c \ub300\uc548\uc758 \ubd80\uc871, \ud658\uc790\uc5d0\uac8c \ud574\ub97c \ub07c\uce60 \uc218 \uc788\ub294 \ubd80\uc871 \uc704\ud5d8\uc131\uc744 \uac15\uc870\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uae00\ub85c\ubc8c \uaddc\uc81c \ud569\uc758 - \uc9c0\uc18d\uc801\uc778 \uc2b9\uc778<\/h3>\n

\uce90\ub098\ub2e4 \ubcf4\uac74\ubd80, \ud638\uc8fc \ub274\uc9c8\ub79c\ub4dc \uc2dd\ud488\ud45c\uc900\uccad(FSANZ), \uc138\uacc4\ubcf4\uac74\uae30\uad6c(WHO), \uc911\uad6d \uad6d\uac00\uc2dd\ud488\uc548\uc804\uc704\ud5d8\ud3c9\uac00\uc13c\ud130(CFSA), \uc77c\ubcf8 \ud6c4\uc0dd\uc131, \uc601\uad6d \ub3c5\uc131\uc704\uc6d0\ud68c\ub294 EU\uc758 \uc2dd\ud488 \ucca8\uac00\ubb3c \uae08\uc9c0\uc5d0 \ub3d9\uc758\ud558\uc9c0 \uc54a\uc73c\uba70 \uc758\uc57d\ud488\uc6a9 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc744 \uacc4\uc18d \uc2b9\uc778\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc758\uc57d\ud488 \uc0ac\uc6a9\uacfc \uc2dd\ud488 \ucca8\uac00\ubb3c \uc0ac\uc6a9\uc774 \ub2e4\ub978 \uc774\uc720<\/h3>\n

\uaddc\uc81c \ub2f9\uad6d\uc774 \uace0\ub824\ud558\ub294 \uba87 \uac00\uc9c0 \uc911\uc694\ud55c \ucc28\uc774\uc810\uc774 \uc788\uc2b5\ub2c8\ub2e4:<\/p>\n

    \n
  • \n

    \ub178\ucd9c \uacbd\ub85c<\/strong>\u00a0- \uc815\uc81c\uc640 \ucea1\uc290\uc740 \ud1b5\uc9f8\ub85c \uc0bc\ud0b5\ub2c8\ub2e4. \ucf54\ud305\uc740 \ub300\ubd80\ubd84 \uadf8\ub300\ub85c \uc720\uc9c0\ub418\uba70 \uc704\uc7a5\uad00\uc5d0\uc11c TiO\u2082 \uc785\uc790\uc758 \uc6a9\ud574 \ub610\ub294 \ubc29\ucd9c\uc774 \ucd5c\uc18c\ud654\ub429\ub2c8\ub2e4.<\/p>\n<\/li>\n

  • \n

    \ubcf5\uc6a9\ub7c9 \ubc0f \uae30\uac04<\/strong>\u00a0- \uc57d\ubb3c \ub178\ucd9c\uc740 \uac04\ud5d0\uc801\uc73c\ub85c \uc815\ud574\uc9c4 \uce58\ub8cc \uae30\uac04 \ub3d9\uc548\ub9cc \uc774\ub8e8\uc5b4\uc9c0\uba70, \ud3c9\uc0dd \ub3d9\uc548 \uc9c0\uc18d\uc801\uc73c\ub85c \uc2dd\ub2e8\uc5d0 \ub178\ucd9c\ub418\ub294 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n<\/li>\n

  • \n

    \uc591\uc2dd<\/strong>\u00a0- \uc81c\uc57d \ub4f1\uae09\uc758 TiO\u2082\ub294 \uc548\ub8cc \ub4f1\uae09\uc73c\ub85c, EFSA \uc2dd\ud488 \ud3c9\uac00\uc5d0\uc11c \uc6b0\ub824\ub97c \ubd88\ub7ec\uc77c\uc73c\ud0a8 \ub098\ub178 \ub4f1\uae09 \ubb3c\uc9c8\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n<\/li>\n

  • \n

    \ub9ac\uc2a4\ud06c-\ud3b8\uc775<\/strong>\u00a0- \uc2dd\ud488 \ucc29\uc0c9\uc81c\uc640 \ub2ec\ub9ac \uc758\uc57d\ud488\uc758 TiO\u2082\ub294 \uc758\uc57d\ud488\uc758 \uc548\uc815\uc131\uacfc \ud658\uc790 \uc548\uc804\uc744 \uc9c1\uc811\uc801\uc73c\ub85c \uc9c0\uc6d0\ud569\ub2c8\ub2e4.<\/p>\n<\/li>\n<\/ul>\n

    \ucea1\uc290 \uc81c\ud615\uc5d0\uc11c \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc5b4\ub5a4 \uc5ed\ud560\uc744 \ud558\ub098\uc694?<\/h2>\n

    \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uacbd\uc9c8 \ubc0f \uc5f0\uc9c8 \ucea1\uc290 \uaecd\uc9c8\uc758 \uc8fc\uc694 \uad6c\uc131 \uc694\uc18c\uc774\uae30\ub3c4 \ud569\ub2c8\ub2e4. \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc758 \uae30\ub2a5\uc740 \uc815\uc81c \ucf54\ud305\uc758 \uae30\ub2a5\uacfc \uc720\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n

    \ucea1\uc290 \uc178\uc758 \ubd88\ud22c\uba85\ub3c4<\/h3>\n

    \uc815\uc81c\uc640 \ub9c8\ucc2c\uac00\uc9c0\ub85c \ud770\uc0c9 \ubd88\ud22c\uba85\ub3c4\ub294 \ud658\uc790\uac00 \ucea1\uc290 \ub0b4\uc6a9\ubb3c\uc744 \ubcfc \uc218 \uc5c6\uac8c \ud569\ub2c8\ub2e4. \ucea1\uc290 \ub0b4\ubd80\uc758 API \uc81c\ud615\uc740 \ub208\uc5d0 \uc798 \ub744\uc9c0 \uc54a\uac70\ub098 \uc0c9\uc0c1\uc774 \ub2e4\uc591\ud558\uac70\ub098 \uc5ec\ub7ec \uac00\uc9c0 \uc0c9\uc0c1\uc758 \uc57d\ubb3c \uc785\uc790\ub97c \ud3ec\ud568\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. TiO\u2082\ub294 \uade0\uc77c\ud55c \uc678\uad00\uc744 \ub9cc\ub4e4\uc5b4 \ub0b4\ubd80\uc758 \uac00\ubcc0\uc131\uc744 \uc228\uae30\uace0 \ud658\uc790\uc758 \uc2e0\ub8b0\ub97c \uad6c\ucd95\ud569\ub2c8\ub2e4.<\/p>\n

    \ucea1\uc290 \ucda9\uc804\uc7ac\uc758 \uc790\uc678\uc120 \ucc28\ub2e8<\/h3>\n

    \ucea1\uc290 \ub0b4\uc6a9\ubb3c\ub3c4 \ube5b\uc5d0 \uc758\ud55c \ud488\uc9c8 \uc800\ud558\uc5d0 \ucde8\uc57d\ud569\ub2c8\ub2e4. \ucea1\uc290 \uc678\ud53c\uc758 TiO\u2082\ub294 \ucda9\uc804\uc7ac\uc5d0 \uc790\uc678\uc120 \ucc28\ub2e8 \uae30\ub2a5\uc744 \uc81c\uacf5\ud558\uc5ec \uad11\uacbd\ud654\uc131 API\uac00 \uc720\ud1b5\uae30\ud55c \ub0b4\ub0b4 \uc548\uc815\uc801\uc73c\ub85c \uc720\uc9c0\ub418\ub3c4\ub85d \ud569\ub2c8\ub2e4.<\/p>\n

    \ud558\ub4dc \ucea1\uc290\uacfc \uc18c\ud504\ud2b8 \ucea1\uc290 - \ubaa8\ub450\uc758 \uc7a5\uc810<\/h3>\n

    \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc824\ub77c\ud2f4\uacfc HPMC \ucea1\uc290 \uaecd\uc9c8 \ubaa8\ub450\uc5d0\uc11c \ud6a8\uacfc\uc801\uc73c\ub85c \uc791\ub3d9\ud569\ub2c8\ub2e4. \ub2e4\uc591\ud55c \uac94\ud654\uc81c\uc640\uc758 \ud638\ud658\uc131 \ubc0f \uac74\uc870 \uc870\uac74\uc5d0\uc11c\uc758 \uc548\uc815\uc131\uc73c\ub85c \uc778\ud574 \ucea1\uc290 \uc81c\uc870\uc5c5\uccb4\uc5d0\uc11c \ub2e4\uc6a9\ub3c4\ub85c \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

    \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uacfc \ub300\uccb4\ud488 - \ube44\uad50 \ud45c<\/h2>\n
    \n\n\n\n\n\n\n\n\n\n\n\n\n
    \ud2b9\uc131<\/th>\nTiO\u2082<\/th>\n\ud0c4\uc0b0\uce7c\uc298<\/th>\n\uc0b0\ud654 \uc544\uc5f0<\/th>\n\ud65c\uc11d<\/th>\n\uc804\ubd84<\/th>\n<\/tr>\n<\/thead>\n
    \ubd88\ud22c\uba85\ub3c4(\ubc1d\uae30)<\/td>\n\ud6cc\ub96d\ud569\ub2c8\ub2e4<\/td>\n\uc911\uac04<\/td>\nGood<\/td>\nPoor<\/td>\n\ub9e4\uc6b0 \uc5f4\uc545\ud568<\/td>\n<\/tr>\n
    \uc790\uc678\uc120 \ucc28\ub2e8<\/td>\n\ud6cc\ub96d\ud569\ub2c8\ub2e4<\/td>\n\ucd5c\uc18c<\/td>\nGood<\/td>\n\uc5c6\uc74c<\/td>\n\uc5c6\uc74c<\/td>\n<\/tr>\n
    \ud654\ud559\uc801 \ubd88\ud65c\uc131<\/td>\n\ud6cc\ub96d\ud569\ub2c8\ub2e4<\/td>\n\uc88b\uc74c(\uc0b0\uc5d0 \ubbfc\uac10\ud568)<\/td>\n\uc911\uac04<\/td>\n\ud6cc\ub96d\ud569\ub2c8\ub2e4<\/td>\nGood<\/td>\n<\/tr>\n
    \uaddc\uc81c \uc218\uc6a9<\/td>\n\uad11\ubc94\uc704(FDA, EMA, WHO)<\/td>\n\uad11\ubc94\uc704<\/td>\n\uc911\uac04<\/td>\n\uad11\ubc94\uc704<\/td>\n\uad11\ubc94\uc704<\/td>\n<\/tr>\n
    kg\ub2f9 \ube44\uc6a9(\ucc38\uc870)<\/td>\nMedium<\/td>\n\ub0ae\uc74c<\/td>\n\uc911\uac04 \ub192\uc74c<\/td>\n\ub0ae\uc74c<\/td>\n\ub0ae\uc74c<\/td>\n<\/tr>\n
    \uad11\ucd09\ub9e4 \uc704\ud5d8<\/td>\n\uc5c6\uc74c(\ucf54\ud305 \ub4f1\uae09)<\/td>\n\uc5c6\uc74c<\/td>\n\ub0ae\uc74c(\ube44\ucf54\ud305)<\/td>\n\uc5c6\uc74c<\/td>\n\uc5c6\uc74c<\/td>\n<\/tr>\n
    \ucea1\uc290 \uc258\uc5d0 \uc801\ud569<\/td>\n\uc608<\/td>\n\uc608(\ubd80\ubd84 \uad50\uccb4)<\/td>\n\uc81c\ud55c\uc801<\/td>\n\uc544\ub2c8\uc694<\/td>\n\uc544\ub2c8\uc694<\/td>\n<\/tr>\n
    EU \uc2dd\ud488 \uae08\uc9c0 \uc601\ud5a5<\/td>\n\ud574\ub2f9 \uc5c6\uc74c<\/td>\n\ud574\ub2f9 \uc5c6\uc74c<\/td>\n\ud574\ub2f9 \uc5c6\uc74c<\/td>\n\ud574\ub2f9 \uc5c6\uc74c<\/td>\n\ud574\ub2f9 \uc5c6\uc74c<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

    \uc8fc\uc694 \uc778\uc0ac\uc774\ud2b8:<\/strong> \ud0c4\uc0b0\uce7c\uc298\uc740 \ud604\uc7ac \ubd88\ud22c\uba85\ub3c4\uac00 \uc720\uc77c\ud55c \uc694\uad6c \uc0ac\ud56d\uc778 \uacbd\uc6b0 TiO\u2082\ub97c \ub300\uccb4\ud560 \uc218 \uc788\ub294 \uac00\uc7a5 \uc2e4\uc6a9\uc801\uc778 \ubc29\ubc95\uc774\uc9c0\ub9cc, \uc790\uc678\uc120 \ucc28\ub2e8 \ud6a8\uacfc\uac00 \ubbf8\ubbf8\ud569\ub2c8\ub2e4. \uc0b0\ud654 \uc544\uc5f0\uc740 \ub354 \ub098\uc740 \uc790\uc678\uc120 \ucc28\ub2e8 \uae30\ub2a5\uc744 \uc81c\uacf5\ud558\uc9c0\ub9cc \ubc1d\uae30\uac00 \ub0ae\uace0 \ube44\uc6a9\uc774 \ub354 \ub192\uc2b5\ub2c8\ub2e4. \ubd88\ud22c\uba85\ub3c4\uc640 \uad11\uc548\uc815\uc131\uc774 \ubaa8\ub450 \ud544\uc694\ud55c \uc560\ud50c\ub9ac\ucf00\uc774\uc158\uc758 \uacbd\uc6b0 TiO\u2082\uc758 \uc131\ub2a5\uc744 \ub2a5\uac00\ud558\ub294 \ub300\uccb4\uc7ac\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

    \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc5b8\uc81c \uc0ac\uc6a9\ud574\uc57c \ud558\ub098\uc694?<\/h2>\n

    \uc774 \uacb0\uc815 \ud504\ub808\uc784\uc6cc\ud06c\ub97c \uc0ac\uc6a9\ud558\uc5ec \uc81c\ud615\uc5d0 TiO\u2082\uac00 \ud544\uc694\ud55c\uc9c0 \uc5ec\ubd80\ub97c \uacb0\uc815\ud558\uc138\uc694.<\/p>\n

    TiO\u2082\ub294 \ub2e4\uc74c\uacfc \uac19\uc740 \uacbd\uc6b0\uc5d0 \uc0ac\uc6a9\ud569\ub2c8\ub2e4:<\/strong><\/p>\n

      \n
    • \n

      API\ub294 \uad11\uc5d0 \ucde8\uc57d\ud558\uba70 \uc790\uc678\uc120 \ucc28\ub2e8\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n<\/li>\n

    • \n

      \ud0dc\ube14\ub9bf \ucf54\uc5b4 \ub610\ub294 \ucea1\uc290 \ucc44\uc6b0\uae30\uc758 \uc0c9\uc0c1\uc774 \ub9e4\ub825\uc801\uc774\uc9c0 \uc54a\uac70\ub098 \uac00\ubcc0\uc801\uc785\ub2c8\ub2e4.<\/p>\n<\/li>\n

    • \n

      \ud0c0\uac9f \uc2dc\uc7a5(\uc608: \ubbf8\uad6d, \uc77c\ubcf8, \uc911\uad6d)\uc5d0\ub294 TiO\u2082\uc5d0 \ub300\ud55c \uc81c\ud55c\uc774 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n

    • \n

      \ud658\uc790\uc758 \uc218\uc6a9\uc131\uacfc \ube0c\ub79c\ub4dc \uc77c\uad00\uc131\uc744 \uc704\ud574 \ubc1d\uc740 \ud770\uc0c9\uc73c\ub85c \ub9c8\uac10\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n<\/li>\n

    • \n

      \uc5ec\ub7ec API\uac00 \ud3ec\ud568\ub41c \ud0dc\ube14\ub9bf\uc744 \uc11c\ub85c \ub2e4\ub978 \uc0c9\uc0c1\uc73c\ub85c \ucf54\ud305\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n<\/ul>\n

      \ud0c4\uc0b0\uce7c\uc298\uacfc \uac19\uc740 \ub300\uccb4\uc81c\ub97c \uace0\ub824\ud558\uc138\uc694:<\/strong><\/p>\n

        \n
      • \n

        API\ub294 \ube5b\uc5d0 \ubbfc\uac10\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n

      • \n

        \ubaa9\ud45c \uc2dc\uc7a5\uc740 EU\uc774\uba70, \uc7a0\uc7ac\uc801\uc778 \uaddc\uc81c\uc5d0 \ub300\ube44\ud558\uc5ec \ubbf8\ub798\ub97c \ub300\ube44\ud558\uace0\uc790 \ud569\ub2c8\ub2e4(\ud604\uc7ac \uc758\uc57d\ud488\uc5d0 \ub300\ud55c \uaddc\uc81c\ub294 \uacc4\ud68d\ub418\uc5b4 \uc788\uc9c0 \uc54a\uc74c).<\/p>\n<\/li>\n

      • \n

        \ub354 \ub0ae\uc740 \ubd88\ud22c\uba85\ub3c4 \ub610\ub294 \ub354 \ub192\uc740 \ucf54\ud305 \ubb34\uac8c\ub97c \uae30\uaebc\uc774 \ubc1b\uc544\ub4e4\uc785\ub2c8\ub2e4.<\/p>\n<\/li>\n

      • \n

        HPMC \ucea1\uc290\uc744 \uc0ac\uc6a9\ud558\ub294 \uc81c\ud615\uc774\uba70 TiO\u2082\uac00 \uc5c6\ub294 \uc635\uc158\uc744 \uc81c\uacf5\ud558\ub294 \uacf5\uae09\uc5c5\uccb4\uc640 \ud611\ub825\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n<\/ul>\n

        TiO\u2082\ub97c \ub300\uccb4\ud560 \uc218 \uc5c6\ub294 \uacbd\uc6b0:<\/strong><\/p>\n

          \n
        • \n

          \ub192\uc740 \ubd88\ud22c\uba85\ub3c4\uc640 \uc790\uc678\uc120 \ucc28\ub2e8\uc774 \ubaa8\ub450 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n<\/li>\n

        • \n

          \ucf54\ud305 \ub450\uaed8\ub294 \uc81c\ud55c\ub418\uc5b4 \uc788\uc73c\uba70 \ub300\uccb4 \ubd88\ud22c\uba85\uc81c\ub97c \ub354 \ub9ce\uc774 \uc0ac\uc6a9\ud558\uc5ec \ubcf4\uc644\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n

        • \n

          \uc81c\ud488\uc774 \uc5ec\ub7ec \uad6d\uac00\uc5d0 \ub4f1\ub85d\ub418\uc5b4 \uc788\ub294 \ub2e4\uad6d\uc801 \ube0c\ub79c\ub4dc\ub85c\uc11c \ubc30\uce58 \uade0\uc77c\uc131\uc774 \ud544\uc694\ud55c \uacbd\uc6b0\uc785\ub2c8\ub2e4.<\/p>\n<\/li>\n<\/ul>\n

          \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc758 \uc8fc\uc694 \ud488\uc9c8 \uae30\uc900\uc740 \ubb34\uc5c7\uc778\uac00\uc694?<\/h2>\n

          \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc5c4\uaca9\ud55c \uc57d\uc804 \uaddc\uaca9\uc744 \ucda9\uc871\ud574\uc57c \ud569\ub2c8\ub2e4. \uc900\uc218 \uc5ec\ubd80\ub97c \ud655\uc778\ud569\ub2c8\ub2e4:<\/p>\n

            \n
          • \n

            \ubbf8\uad6d \uc57d\uc804(USP)\/\uad6d\uac00 \uacf5\uc804(NF)<\/strong>\u00a0- \ubd80\ud615\uc81c\ub85c\uc11c TiO\u2082\uc5d0 \ub300\ud55c \uacf5\uc2dd \ub17c\ubb38.<\/p>\n<\/li>\n

          • \n

            \uc720\ub7fd \uc57d\uc804(EP\/Ph. Eur.)<\/strong>\u00a0- \uc21c\ub3c4 \ud14c\uc2a4\ud2b8, \uc911\uae08\uc18d \uc81c\ud55c, \uc785\uc790 \ud06c\uae30.<\/p>\n<\/li>\n

          • \n

            \uc77c\ubcf8 \uc57d\uc804(JP)<\/strong> - \uc77c\ubcf8 \uc2dc\uc7a5\uc5d0 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n<\/li>\n

          • \n

            \uc911\uad6d \uc57d\uc804(ChP)<\/strong> - \uc911\uad6d \uc2dc\uc7a5\uc5d0 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n<\/li>\n<\/ul>\n

            \uc77c\ubc18\uc801\uc778 \uc0ac\uc591\uc785\ub2c8\ub2e4:<\/p>\n

            \n\n\n\n\n\n\n\n\n\n\n\n
            \ub9e4\uac1c\ubcc0\uc218<\/th>\n\uc0ac\uc591<\/th>\n<\/tr>\n<\/thead>\n
            TiO\u2082 \ud568\ub7c9(\uac74\uc870 \uae30\uc900)<\/td>\n98.0-100.5%<\/td>\n<\/tr>\n
            \uc911\uae08\uc18d(\ub0a9)<\/td>\n\u226420ppm<\/td>\n<\/tr>\n
            \ube44\uc18c(As)<\/td>\n\u22645ppm<\/td>\n<\/tr>\n
            \ucca0(Fe)<\/td>\n\u22640.02%<\/td>\n<\/tr>\n
            \uc218\uc6a9\uc131 \ubb3c\uc9c8<\/td>\n\u22640.25%<\/td>\n<\/tr>\n
            \uac74\uc870 \uc2dc \uc190\uc2e4<\/td>\n\u22640.5%<\/td>\n<\/tr>\n
            \ucd1d \ubc15\ud14c\ub9ac\uc544 \uc218<\/td>\n<1000 cfu\/g<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284 \uacf5\uae09\uc5c5\uccb4\ub97c \uc120\ud0dd\ud558\ub294 \ubc29\ubc95<\/h2>\n

            \ub2e4\uc74c \ub2e8\uacc4\uc5d0 \ub530\ub77c \uaddc\uc815\uc744 \uc900\uc218\ud558\uace0 \ubc30\uce58 \uac04 \uc77c\uad00\uc131\uc744 \ubcf4\uc7a5\ud558\uc138\uc694.<\/p>\n

            \uc57d\uc804 \uaddc\uc815 \uc900\uc218 \ud655\uc778<\/h3>\n

            \uc81c\ud488\uc774 \ud0c0\uac9f \uc2dc\uc7a5\uc5d0\uc11c \uc694\uad6c\ud558\ub294 USP-NF, EP, JP \ubc0f\/\ub610\ub294 ChP \ud45c\uc900\uc744 \ucda9\uc871\ud558\ub294\uc9c0 \ud655\uc778\ud569\ub2c8\ub2e4. \uae00\ub85c\ubc8c \uc720\ud1b5\uc744 \uc704\ud574\uc11c\ub294 \uc5ec\ub7ec \uc778\uc99d\uc744 \ubc1b\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4.<\/p>\n

            \ubd84\uc11d \uc778\uc99d\uc11c(COA) \uac80\ud1a0<\/h3>\n

            TiO\u2082 \ud568\ub7c9, \uc911\uae08\uc18d, \ube44\uc18c, \ucca0, \uc218\uc6a9\uc131 \ubb3c\uc9c8 \ubc0f \ubbf8\uc0dd\ubb3c \ud55c\ub3c4\uc758 \ubc30\uce58 \uac04 \uc77c\uad00\uc131\uc744 \ud655\uc778\ud569\ub2c8\ub2e4. \uc2e4\uc81c \ud14c\uc2a4\ud2b8 \uac12\uc744 \ubcf4\uace0\ud558\ub294 COA\ub97c \ucc3e\uc544\ubcf4\uc138\uc694.<\/p>\n

            \uc785\uc790 \ud06c\uae30 \ubd84\ud3ec \ud3c9\uac00<\/h3>\n

            \uc785\uc790 \ud06c\uae30\ub294 \ubd88\ud22c\uba85\ub3c4, \ucf54\ud305 \uade0\uc77c\uc131 \ubc0f \ubd84\uc0b0\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uc77c\uad00\ub41c \ubbf8\uc138 \uc785\uc790 \ud06c\uae30(\uc608: d50 ~0.8 \u03bcm)\ub294 \ub9e4\ub044\ub7ec\uc6b4 \ucf54\ud305 \ud45c\uba74\uc744 \ubcf4\uc7a5\ud569\ub2c8\ub2e4.<\/p>\n

            \uaddc\uc815 \ubb38\uc11c \ud3c9\uac00<\/h3>\n

            ANDA, NDA \ub610\ub294 DMF \uc81c\ucd9c\uc758 \uacbd\uc6b0 \uacf5\uae09\uc5c5\uccb4\uac00 \uc720\ud615 III \uc758\uc57d\ud488 \ub9c8\uc2a4\ud130 \ud30c\uc77c(DMF) \ub610\ub294 \uc801\ud569\uc131 \uc99d\uba85\uc11c(CEP)\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\ub294\uc9c0 \ud655\uc778\ud569\ub2c8\ub2e4. \uc81c\uc870 \uc0ac\uc774\ud2b8\uac00 FDA, EMA \ub610\ub294 NMPA\uc5d0 \uc801\uc808\ud558\uac8c \ub4f1\ub85d\ub418\uc5b4 \uc788\ub294\uc9c0 \ud655\uc778\ud569\ub2c8\ub2e4.<\/p>\n

            \ud488\uc9c8 \uc2dc\uc2a4\ud15c \uac10\uc0ac<\/h3>\n

            ISO 9001 \uc778\uc99d\uacfc \uace0\uc704\ud5d8 \uc2dc\uc7a5\uc758 \uacbd\uc6b0 ISO 15378(\uc758\uc57d\ud488\uc758 1\ucc28 \ud3ec\uc7a5\uc7ac) \ub610\ub294 \uc758\uc57d\ud488 \ubd80\ud615\uc81c\uc5d0 \ub300\ud55c cGMP \uc900\uc218 \uc5ec\ubd80\ub97c \ud655\uc778\ud569\ub2c8\ub2e4.<\/p>\n

            \uc2dc\uc7a5 \uc804\ub9dd\uacfc \uc81c\uc57d \ubd84\uc57c\uc5d0\uc11c\uc758 TiO\u2082\uc758 \ubbf8\ub798<\/h2>\n

            \uc804 \uc138\uacc4 \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284 \uc2dc\uc7a5\uc740 2025\ub144 \uc57d 2\uc5b5 2,050\ub9cc \ub2ec\ub7ec\ub85c \ucd94\uc815\ub418\uba70 4.75%\uc758 \uc5f0\ud3c9\uade0 \uc131\uc7a5\ub960\ub85c \uc131\uc7a5\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \uc218\uc694 \ub3d9\uc778\uc73c\ub85c\ub294 \uc81c\uc57d \uc0dd\uc0b0 \uc99d\uac00, \ub9cc\uc131 \uc9c8\ud658 \uc720\ubcd1\ub960 \uc99d\uac00, \uc2e0\ud765 \uacbd\uc81c\uad6d\uc758 \uc758\ub8cc \uc811\uadfc\uc131 \ud655\ub300 \ub4f1\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

            \ud604\uc7ac \ud0c4\uc0b0\uce7c\uc298\uc774 \uac00\uc7a5 \uc2e4\uc6a9\uc801\uc778 \ub300\uc548\uc73c\ub85c \uc5ec\uaca8\uc9c0\ub294 \ub4f1 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284 \ub300\uccb4\uc81c\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \ud65c\ubc1c\ud788 \uc9c4\ud589\ub418\uace0 \uc788\uc9c0\ub9cc, \uad11\ud559\uc801 \uc131\ub2a5, \ud654\ud559\uc801 \uc548\uc815\uc131, \uad11\ubc94\uc704\ud55c \uaddc\uc81c \uc218\uc6a9\uc131\uc744 \ubaa8\ub450 \uac16\ucd98 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc758 \uc870\ud569\uc744 \ub530\ub77c\uc7a1\uc744 \ub9cc\ud55c \ub2e8\uc77c \uc7ac\ub8cc\ub294 \uc544\uc9c1 \uc5c6\uc2b5\ub2c8\ub2e4. \ub2f9\ubd84\uac04 \uc81c\uc57d \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc815\uc81c \ubc0f \ucea1\uc290 \uc81c\ud615\uc5d0 \uac00\uc7a5 \ub9ce\uc774 \uc0ac\uc6a9\ub418\ub294 \ubd80\ud615\uc81c\ub85c \ub0a8\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

            \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38(\uac80\uc0c9 \ucd5c\uc801\ud654)<\/h2>\n

            Q1: \ud0dc\ube14\ub9bf \ucf54\ud305\uc5d0 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc774 \uc0ac\uc6a9\ub418\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc778\uac00\uc694?<\/strong>
            \n\ubd88\ud22c\uba85\ub3c4(\uc815\uc81c \ucf54\uc5b4\ub97c \uac00\ub9bc), \uc790\uc678\uc120 \ucc28\ub2e8(API \uc800\ud558 \ubc29\uc9c0), \ud658\uc790\ub4e4\uc774 \uae30\ub300\ud558\ub294 \ud770\uc0c9 \ub9c8\uac10\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \ucd5c\uace0\uc758 \ubd88\ud22c\uba85\uc81c\uc785\ub2c8\ub2e4.<\/p>\n

            Q2: \uc758\uc57d\ud488 \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc0bc\ucf1c\ub3c4 \uc548\uc804\ud55c\uac00\uc694?<\/strong>
            \n\uc608. \ubbf8\uad6d FDA, EMA(2025\ub144 \uc7ac\ud655\uc778), \uce90\ub098\ub2e4 \ubcf4\uac74\ubd80, WHO, \uc911\uad6d CFSA\ub97c \ud3ec\ud568\ud55c \uae00\ub85c\ubc8c \uaddc\uc81c \uae30\uad00\uc5d0\uc11c \uc758\uc57d\ud488\uc73c\ub85c \uc0ac\uc6a9\uc744 \uc2b9\uc778\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. EU \uc2dd\ud488 \uae08\uc9c0 \uaddc\uc815\uc740 \uc758\uc57d\ud488\uc5d0\ub294 \uc801\uc6a9\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

            Q3: \uc81c\uc57d \ub4f1\uae09\uacfc \uc0b0\uc5c5\uc6a9 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc758 \ucc28\uc774\uc810\uc740 \ubb34\uc5c7\uc778\uac00\uc694?<\/strong>
            \n\uc81c\uc57d \ub4f1\uae09\uc740 \uc5c4\uaca9\ud55c \uc57d\uc804 \uc21c\ub3c4 \uc81c\ud55c(98.0-100.5% TiO\u2082), \uc911\uae08\uc18d \u226420ppm, \ube44\uc18c \u22645ppm \ubc0f \ubbf8\uc0dd\ubb3c \uc81c\ud55c\uc744 \ucda9\uc871\ud569\ub2c8\ub2e4. \uc0b0\uc5c5\uc6a9 \ub4f1\uae09\uc740 \uc21c\ub3c4\uac00 \ub0ae\uace0 \uc548\uc804 \uad00\ub9ac\uac00 \ub354 \uc801\uc2b5\ub2c8\ub2e4.<\/p>\n

            Q4: \ucea1\uc290\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc744 \ud0c4\uc0b0\uce7c\uc298\uc73c\ub85c \ub300\uccb4\ud560 \uc218 \uc788\ub098\uc694?<\/strong>
            \n\ubd80\ubd84\uc801\uc73c\ub85c. \ud0c4\uc0b0\uce7c\uc298\uc740 \uc801\ub2f9\ud55c \ubd88\ud22c\uba85\ub3c4\ub97c \uc81c\uacf5\ud558\uc9c0\ub9cc \uc790\uc678\uc120 \ucc28\ub2e8 \ud6a8\uacfc\ub294 \ubbf8\ubbf8\ud569\ub2c8\ub2e4. \uad11\uacbd\ud654\uc131 API\uc758 \uacbd\uc6b0 TiO\u2082\uac00 \uc5ec\uc804\ud788 \uc6b0\uc218\ud569\ub2c8\ub2e4. \ube5b\uc5d0 \ubbfc\uac10\ud558\uc9c0 \uc54a\uc740 \uc57d\ud488\uc758 \uacbd\uc6b0, \uc720\ub7fd \uc2dc\uc7a5\uc774 \uc6b0\ub824\ub418\ub294 \uacbd\uc6b0 \ud0c4\uc0b0\uce7c\uc298\uc774 \ub300\uc548\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

            Q5: \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc758 \uc0d8\ud50c \ub610\ub294 \uc0ac\uc591\uc11c\ub294 \uc5b4\ub5bb\uac8c \uc694\uccad\ud558\ub098\uc694?<\/strong>
            \n\uc81c\uc870\uc5c5\uccb4\uc5d0 \uc9c1\uc811 \ubb38\uc758\ud558\uc138\uc694. \ud3c9\ud310\uc774 \uc88b\uc740 \uacf5\uae09\uc5c5\uccb4\ub294 \ubc30\uce58\ubcc4 COA, \uae30\uc220 \ub370\uc774\ud130 \uc2dc\ud2b8, DMF \uc9c0\uc6d0 \ubc0f \uc81c\ud615 \ud14c\uc2a4\ud2b8\ub97c \uc704\ud55c \uc0d8\ud50c\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

            \uacb0\ub860<\/h2>\n

            \uc81c\uc57d \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc815\uc81c \ubc0f \ucea1\uc290 \uc81c\ud615\uc5d0 \uc5c6\uc5b4\uc11c\ub294 \uc548 \ub420 \ubd80\ud615\uc81c\ub85c \ub0a8\uc544 \uc788\uc2b5\ub2c8\ub2e4. \ub300\ubd80\ubd84\uc758 \uae00\ub85c\ubc8c \uc2dc\uc7a5\uc5d0\uc11c \ud0c1\uc6d4\ud55c \ubd88\ud22c\uba85\ub3c4, \uc790\uc678\uc120 \ucc28\ub2e8, \ud658\uc790 \uc218\uc6a9\uc131, \uaddc\uc81c \uc218\uc6a9\uc131\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc720\ub7fd\uc5f0\ud569 \uc9d1\ud589\uc704\uc6d0\ud68c\uac00 2025\ub144\uae4c\uc9c0 \uc758\uc57d\ud488\uc5d0\uc11c \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284 \uc0ac\uc6a9\uc744 \uc7ac\ud655\uc778\ud55c \uac83\uc740 \uc774 \ubb3c\uc9c8\uc758 \uc9c0\uc18d\uc801\uc778 \uc911\uc694\uc131\uc744 \uac15\uc870\ud55c \uac83\uc785\ub2c8\ub2e4. \ud0c4\uc0b0\uce7c\uc298\uacfc \uac19\uc740 \ub300\uccb4 \uc18c\uc7ac\uac00 \ud2c8\uc0c8 \uc6a9\ub3c4\ub85c \uc874\uc7ac\ud558\uc9c0\ub9cc, \ubaa8\ub4e0 \ud575\uc2ec \uae30\ub2a5\uc5d0\uc11c TiO\u2082\uc758 \uc131\ub2a5\uc744 \ub2a5\uac00\ud558\ub294 \ub2e8\uc77c \uc18c\uc7ac\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

            \uc815\uc81c \ucf54\ud305 \ub610\ub294 \ucea1\uc290 \uc81c\ud615\uc744 \uc704\ud55c \uc81c\uc57d \ub4f1\uae09 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc744 \uacf5\uae09\ud560 \uc900\ube44\uac00 \ub418\uc168\ub098\uc694? \uac15\uc18c \ud6c4\uc13c \ud2f0\ud0c0\ub284 \ud654\uc774\ud2b8 \ud14c\ud06c\ub180\ub85c\uc9c0 \uc720\ud55c\ud68c\uc0ac\ub294 20\ub144 \uc774\uc0c1 \uc758\uc57d\uc6a9 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284 \uc0dd\uc0b0\uc744 \uc804\ubb38\uc73c\ub85c \ud574\uc654\uc2b5\ub2c8\ub2e4. \uc81c\ud488\uc740 \uc911\uad6d \uc57d\uc804, \ubbf8\uad6d FDA \uc57d\uc804 \ubc0f \uc720\ub7fd EP \uc57d\uc804 \ud45c\uc900\uc744 \ucda9\uc871\ud569\ub2c8\ub2e4.<\/p>\n

            \uc5b8\uc81c\ub4e0\uc9c0 \ubb38\uc758\ud558\uae30<\/strong><\/a> \uc5b8\uc81c\ub4e0\uc9c0 \ubb38\uc758\ud558\uc138\uc694.<\/p>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

            \uc81c\uc57d \ub4f1\uae09\uc758 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc740 \uc815\uc81c \ucf54\ud305\uacfc \ucea1\uc290 \uaecd\uc9c8\uc5d0\uc11c \ubd88\ud22c\uba85\uc81c \ubc0f \ubc31\uc0c9 \uc548\ub8cc\ub85c \uc0ac\uc6a9\ub418\ub294 \uc911\uc694\ud55c \ubd80\ud615\uc81c\uc785\ub2c8\ub2e4. \uc774 \uac00\uc774\ub4dc\uc5d0\uc11c\ub294 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uc744 \uc0ac\uc6a9\ud558\ub294 \uc774\uc720, \uc548\uc804\uc131 \ubb38\uc81c, \ub300\uccb4 \uc635\uc158 \ubc0f \uc81c\uc870\uc5c5\uccb4\uc758 \uc120\ud0dd \uae30\uc900\uc5d0 \ub300\ud574 \uc124\uba85\ud569\ub2c8\ub2e4.<\/p>","protected":false},"author":1,"featured_media":671,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[155,153,118,154,156],"class_list":["post-888","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news","tag-capsule-formulation","tag-pharmaceutical-excipient","tag-pharmaceutical-grade-titanium-dioxide","tag-tablet-coating","tag-titanium-dioxide-in-drugs"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/posts\/888","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/comments?post=888"}],"version-history":[{"count":0,"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/posts\/888\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/media\/671"}],"wp:attachment":[{"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/media?parent=888"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/categories?post=888"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hushentitanium.com\/ko\/wp-json\/wp\/v2\/tags?post=888"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}